PDF(Pubmed)
Abstract：
Aneurysmal bone cyst (ABC) is a non-malignant, locally destructive, blood-filled lesion in the bone that tends to grow aggressively. A young girl presented with a rapid recurrence after aggressive surgery of a large symptomatic sacral-spinal ABC. After a multidisciplinary tumour board, she was successfully treated with sclerotherapy and monthly intravenous denosumab. The patient has maintained asymptomatic for over 36 months now and has returned to full activity and strength. She never required surgery and has had radiologic resolution of the lesions. Treatment of recurrent ABC requires a multidisciplinary team approach. We believe this to be the first report to use this combined therapy to provide an alternative to morbid surgery for children with ABCs.
摘要：
动脉瘤性骨囊肿（ABC）是非恶性的，局部破坏性的，骨骼中充满血液的病变，倾向于剧烈生长。一名年轻女孩在对有症状的大型骶椎ABC进行积极手术后迅速复发。在多学科肿瘤委员会之后，她成功地接受了硬化治疗和每月静脉注射denosumab。患者现在已经保持无症状超过36个月，并且已经恢复到完全的活动和力量。她从未需要手术，并且已经对病变进行了放射学处理。复发性ABC的治疗需要多学科的团队方法。我们认为这是第一份使用这种联合疗法为儿童ABC提供病态手术的替代方法的报告。
