关键词: Biopsia Biopsy Immunomodulation Inflamación Inflammation Inmunomodulación Keratoconjunctivitis Lichen planus Liquen plano Queratoconjuntivitis

Mesh : Humans Female Aged Lichen Planus / complications drug therapy Keratoconjunctivitis / etiology drug therapy complications Cicatrix / etiology complications Immunosuppressive Agents / therapeutic use

来  源:   DOI:10.1016/j.oftale.2024.04.002

Abstract:
The aim of this article is to report clinical features and therapeutic approach of cicatrizing keratoconjunctivitis secondary to ocular lichen planus based on a case report. The patient is a 77-year-old female with a history of ocular discomfort and recurrent keratoconjunctivitis that did not improve with conservative treatment, as well as a history of oral and nasal aphthous ulcers. After a complete ophthalmologic, dermatologic and anatomopathological study, the diagnosis of ocular lichen planus was established and immunosuppressive treatment was initiated. Most cases of ocular lichen planus are presented as chronic cicatricial conjunctivitis. A correct differential diagnosis, as well as an early detection are essential for the control of this entity and its sequelae. Treatment, based on corticosteroids and immunosuppressants, both topical and systemic, is aimed at controlling inflammation and scarring.
摘要:
本文的目的是根据一例病例报告,报告眼部扁平苔藓继发的瘢痕性角膜结膜炎的临床特征和治疗方法。患者为一名77岁女性,有眼部不适及复发性角膜结膜炎病史,经保守治疗后并未好转,以及口腔和鼻腔阿弗他溃疡的病史。完成眼科检查后,皮肤病学和解剖病理学研究,建立了眼部扁平苔藓的诊断,并开始了免疫抑制治疗。大多数眼部扁平苔藓病例表现为慢性瘢痕性结膜炎。正确的鉴别诊断,以及早期发现对于控制该实体及其后遗症至关重要。治疗,基于皮质类固醇和免疫抑制剂,局部和全身,旨在控制炎症和疤痕。
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