关键词: bisphosphonates distal end radius giant cell tumor intralesional curettage zoledronic acid

来  源:   DOI:10.7759/cureus.55794   PDF(Pubmed)

Abstract:
Giant cell tumors are benign yet locally aggressive neoplasms commonly observed in the distal radius, exhibiting higher recurrence rates compared to other tumor types. This study presents a case involving a 50-year-old farmer who presented with swelling at the distal end of his wrist. The patient underwent treatment involving intralesional curettage and supplementation with zoledronic acid, resulting in a significant reduction in the tumor\'s potential for recurrence. This approach aims to achieve an optimal balance between functional outcomes and disease management in the majority of cases. While this strategy proves effective in most instances, there may be scenarios where resection becomes imperative due to the severity of the disease, ensuring adequate disease clearance. In such circumstances, judicious decision-making coupled with an appropriate treatment plan is crucial to guarantee a satisfactory outcome, even in the face of challenges.
摘要:
巨细胞瘤是通常在桡骨远端观察到的良性但局部侵袭性肿瘤。与其他肿瘤类型相比,复发率更高。这项研究提出了一个案例,涉及一名50岁的农民,他的手腕远端肿胀。患者接受了包括病灶内刮治和补充唑来膦酸的治疗,导致肿瘤复发的可能性显着降低。这种方法旨在在大多数情况下实现功能结果和疾病管理之间的最佳平衡。虽然这种策略在大多数情况下被证明是有效的,在某些情况下,由于疾病的严重程度,切除手术变得势在必行,确保足够的疾病清除。在这种情况下,明智的决策以及适当的治疗计划对于保证令人满意的结果至关重要,即使面对挑战。
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