PDF(Pubmed)
Abstract：
Dengue fever (DF), which is caused by the dengue virus (DENV) and transmitted through Aedes mosquitoes, is well recognized for its systemic manifestations, with its ocular involvement gaining recent attention. We present a case of a 41-year-old Taiwanese female who developed acute macular neuroretinopathy (AMN) following a DF diagnosis related to DENV-1, emphasizing the need for awareness of this complication. The patient, with a history of completely resolved optic neuritis (ON) and comorbidities, experienced blurred vision on day 10 after the onset of DF. The ophthalmic examination revealed macular edema, ellipsoid zone (EZ) infiltration, and choriocapillaris involvement. Despite pulse therapy with corticosteroids, visual disturbances persisted, highlighting the challenge of managing ocular complications. Ocular manifestations in DF include hemorrhages, inflammation, and vascular complications. DF-associated AMN, a rare presentation, poses challenges in diagnosis and treatment response evaluation. While most patients recover spontaneously, some face persistent visual impairment, especially with AMN. Our case emphasizes the importance of recognizing ocular complications in DF, necessitating a multidisciplinary approach for optimal management and further research to delineate treatment strategies and outcomes.
摘要：
登革热（DF），由登革热病毒（DENV）引起并通过伊蚊传播，因其系统性表现而广为人知，它的眼部受累最近引起了人们的注意。我们介绍了一例41岁的台湾女性，该女性在与DENV-1相关的DF诊断后发展为急性黄斑神经视网膜病变（AMN），强调需要意识到这种并发症。病人,有完全消退的视神经炎（ON）和合并症的病史，在DF发作后第10天出现视力模糊。眼科检查显示黄斑水肿,椭球带(EZ)入渗,和脉络膜包膜受累。尽管用皮质类固醇进行脉冲治疗，视觉障碍持续存在，突出了管理眼部并发症的挑战。DF的眼部表现包括出血，炎症,血管并发症。DF相关AMN,一个罕见的演讲，在诊断和治疗反应评估中提出了挑战。虽然大多数患者自发康复，有些人面临持续性视力障碍，尤其是AMN。我们的案例强调了认识到DF中眼部并发症的重要性，需要采用多学科方法进行最佳管理和进一步研究，以描绘治疗策略和结果。
