Abstract：
UNASSIGNED: Hypertriglyceridemic waist (HW), hypertriglyceridemic waist-to-height ratio (HWHtR), and waist-to-hip ratio (WHR) have been shown to be indicators of cardiometabolic risk factors. However, it is not clear which indicator is more suitable for children and adolescents. We aimed to investigate the relationship between HW, HWHtR, WHR, and cardiovascular risk factors clustering to determine the best screening tools for cardiometabolic risk in children and adolescents.
UNASSIGNED: This was a national cross-sectional study. Anthropometric and biochemical variables were assessed in approximately 70,000 participants aged 6-18 years from seven provinces in China. Demographics, physical activity, dietary intake, and family history of chronic diseases were obtained through questionnaires. ANOVA, χ 2 and logistic regression analysis was conducted.
UNASSIGNED: A significant sex difference was observed for HWHtR and WHR, but not for HW phenotype. The risk of cardiometabolic health risk factor clustering with HW phenotype or the HWHtR phenotype was significantly higher than that with the non-HW or non-HWHtR phenotypes among children and adolescents (HW: OR = 12.22, 95% CI: 9.54-15.67; HWHtR: OR = 9.70, 95% CI: 6.93-13.58). Compared with the HW and HWHtR phenotypes, the association between risk of cardiometabolic health risk factors (CHRF) clustering and high WHR was much weaker and not significant (WHR: OR = 1.14, 95% CI: 0.97-1.34).
UNASSIGNED: Compared with HWHtR and WHR, the HW phenotype is a more convenient indicator withhigher applicability to screen children and adolescents for cardiovascular risk factors.
UNASSIGNED: This was a national cross-sectional study. Anthropometric and biochemical variables were assessed in approximately 70,000 participants aged 6-18 years from seven provinces in China. Demographics, physical activity, dietary intake, and family history of chronic diseases were obtained through questionnaires. ANOVA, χ 2 and logistic regression analysis was conducted.
UNASSIGNED: A significant sex difference was observed for HWHtR and WHR, but not for HW phenotype. The risk of cardiometabolic health risk factor clustering with HW phenotype or the HWHtR phenotype was significantly higher than that with the non-HW or non-HWHtR phenotypes among children and adolescents (HW: OR = 12.22, 95% CI: 9.54-15.67; HWHtR: OR = 9.70, 95% CI: 6.93-13.58). Compared with the HW and HWHtR phenotypes, the association between risk of cardiometabolic health risk factors (CHRF) clustering and high WHR was much weaker and not significant (WHR: OR = 1.14, 95% CI: 0.97-1.34).
UNASSIGNED: Compared with HWHtR and WHR, the HW phenotype is a more convenient indicator withhigher applicability to screen children and adolescents for cardiovascular risk factors.
摘要：
■高甘油三酯腰围（HW），高甘油三酯腰围与身高比（HWHtR），和腰臀比(WHR)已被证明是心脏代谢危险因素的指标.然而,尚不清楚哪种指标更适合儿童和青少年。我们的目的是调查HW，HWHtR,WHR,和心血管危险因素聚类，以确定儿童和青少年心脏代谢风险的最佳筛查工具。
■这是一项全国性的横断面研究。在中国七个省份的大约70,000名6-18岁的参与者中评估了人体测量和生化变量。人口统计,身体活动,饮食摄入量，通过问卷调查获得慢性病家族史。方差分析,进行χ2和logistic回归分析。
■观察到HWHtR和WHR的显着性别差异，但不是针对HW表型。在儿童和青少年中，HW表型或HWHtR表型的心脏代谢健康危险因素聚集的风险显着高于非HW或非HWHtR表型的风险（HW：OR=12.22，95％CI：9.54-15.67；HWHtR：OR=9.70，95％CI：6.93-13.58）。与HW和HWHtR表型相比，心脏代谢健康危险因素(CHRF)聚集风险与高WHR之间的关联更弱且不显著(WHR:OR=1.14,95%CI:0.97~1.34).
■与HWHtR和WHR相比，HW表型是一个更方便的指标,更适用于儿童和青少年的心血管危险因素筛查.
■这是一项全国性的横断面研究。在中国七个省份的大约70,000名6-18岁的参与者中评估了人体测量和生化变量。人口统计,身体活动,饮食摄入量，通过问卷调查获得慢性病家族史。方差分析,进行χ2和logistic回归分析。
■观察到HWHtR和WHR的显着性别差异，但不是针对HW表型。在儿童和青少年中，HW表型或HWHtR表型的心脏代谢健康危险因素聚集的风险显着高于非HW或非HWHtR表型的风险（HW：OR=12.22，95％CI：9.54-15.67；HWHtR：OR=9.70，95％CI：6.93-13.58）。与HW和HWHtR表型相比，心脏代谢健康危险因素(CHRF)聚集风险与高WHR之间的关联更弱且不显著(WHR:OR=1.14,95%CI:0.97~1.34).
■与HWHtR和WHR相比，HW表型是一个更方便的指标,更适用于儿童和青少年的心血管危险因素筛查.
