PDF(Pubmed)
Abstract：
UNASSIGNED: Idiopathic granulomatous mastitis is an uncommon, long-lasting inflammatory condition of the female breast. It is characterized by the development of a painful breast mass that gradually increases in size. This condition is benign and its cause is unknown. It primarily affects women of childbearing age who have a history of pregnancy and breastfeeding. The main feature of idiopathic granulomatous mastitis is the presence of chronic inflammation in the breast.
METHODS: We report a 36-year-old woman with a history of pregnancy and breastfeeding presented with pain and swelling of the right breast. Physical examination revealed a mass with redness and retraction of the nipple. Imaging revealed localized density and hypoechoic areas with collection, suggesting granulomatous mastitis. A biopsy confirmed the diagnosis. The abscess was drained through a small incision performed under local anesthesia. Treatment with corticosteroids resulted in significant improvement, with complete resolution after one month.
UNASSIGNED: A comprehensive evaluation of potential causes is necessary to confirm the diagnosis of idiopathic granulomatous mastitis. Histologically, it is distinguished by the predominant presence of neutrophils and the absence of caseous necrosis. Treatment remains controversial, with recent literature supporting the efficacy of conservative management with steroid and immunosuppressive therapy, leaving surgical excision for complicated and refractory cases.
CONCLUSIONS: Idiopathic granulomatous mastitis is an uncommon breast condition where the exact causes and recommended treatment approaches are not well-defined. It is important to consider this condition in women who are in their reproductive years.
METHODS: We report a 36-year-old woman with a history of pregnancy and breastfeeding presented with pain and swelling of the right breast. Physical examination revealed a mass with redness and retraction of the nipple. Imaging revealed localized density and hypoechoic areas with collection, suggesting granulomatous mastitis. A biopsy confirmed the diagnosis. The abscess was drained through a small incision performed under local anesthesia. Treatment with corticosteroids resulted in significant improvement, with complete resolution after one month.
UNASSIGNED: A comprehensive evaluation of potential causes is necessary to confirm the diagnosis of idiopathic granulomatous mastitis. Histologically, it is distinguished by the predominant presence of neutrophils and the absence of caseous necrosis. Treatment remains controversial, with recent literature supporting the efficacy of conservative management with steroid and immunosuppressive therapy, leaving surgical excision for complicated and refractory cases.
CONCLUSIONS: Idiopathic granulomatous mastitis is an uncommon breast condition where the exact causes and recommended treatment approaches are not well-defined. It is important to consider this condition in women who are in their reproductive years.
摘要：
■特发性肉芽肿性乳腺炎并不常见，女性乳房的长期炎症状况。它的特征是疼痛的乳房肿块的发展，其大小逐渐增加。这种情况是良性的，原因不明。它主要影响有怀孕和母乳喂养史的育龄妇女。特发性肉芽肿性乳腺炎的主要特征是乳房中存在慢性炎症。
方法：我们报告了一名36岁女性，有妊娠和哺乳史，右侧乳房疼痛和肿胀。体格检查显示肿块，乳头发红和缩回。成像显示局部密度和低回声区域与收集，提示肉芽肿性乳腺炎.活检证实了诊断。在局部麻醉下通过小切口引流脓肿。用皮质类固醇治疗导致显着改善，一个月后完成决议。
■必须对潜在原因进行全面评估，以确认特发性肉芽肿性乳腺炎的诊断。组织学上,它的特点是主要存在中性粒细胞和不存在干酪样坏死。治疗仍然存在争议，最近的文献支持保守治疗与类固醇和免疫抑制治疗的疗效，对复杂和难治性病例进行手术切除。
结论：特发性肉芽肿性乳腺炎是一种罕见的乳腺疾病，其确切原因和推荐的治疗方法尚不明确。重要的是要考虑到处于生育期的女性的这种情况。
方法：我们报告了一名36岁女性，有妊娠和哺乳史，右侧乳房疼痛和肿胀。体格检查显示肿块，乳头发红和缩回。成像显示局部密度和低回声区域与收集，提示肉芽肿性乳腺炎.活检证实了诊断。在局部麻醉下通过小切口引流脓肿。用皮质类固醇治疗导致显着改善，一个月后完成决议。
■必须对潜在原因进行全面评估，以确认特发性肉芽肿性乳腺炎的诊断。组织学上,它的特点是主要存在中性粒细胞和不存在干酪样坏死。治疗仍然存在争议，最近的文献支持保守治疗与类固醇和免疫抑制治疗的疗效，对复杂和难治性病例进行手术切除。
结论：特发性肉芽肿性乳腺炎是一种罕见的乳腺疾病，其确切原因和推荐的治疗方法尚不明确。重要的是要考虑到处于生育期的女性的这种情况。
