Abstract：
Skin tumors commonly seen in dermatology are involved in all layers of the skin and appendages. While biopsy of affected skin remains an essential method to confirm diagnosis and to predicate tumor prognosis, it has its limitations. Recently, photodynamic diagnosis (PDD) has demonstrated high sensitivity in detecting affected skin and mucosal tissues, providing valuable guidance for precision surgery to resect skin and mucosal tumors. In this review, we summarized the literatures concerning the applications of PDD in diagnostic process and treatment of skin and mucosal conditions such as actinic keratoses (AK), basal cell carcinoma (BCC), squamous cell carcinoma (SCC), Bowen\'s disease (BD) and extramammary Paget\'s disease (EMPD). The findings suggest that PDD holds substantial promise for expanding clinical applications and deserves further research exploration.
摘要：
■皮肤病学中常见的皮肤肿瘤涉及皮肤和附件的所有层。虽然受影响的皮肤活检仍然是确认诊断和预测肿瘤预后的重要方法，它有其局限性。最近,光动力诊断（PDD）在检测受影响的皮肤和粘膜组织方面表现出高灵敏度，为精准手术切除皮肤和粘膜肿瘤提供有价值的指导。在这次审查中,综述了PDD在光化性角化病(AK)等皮肤黏膜疾病的诊断过程和治疗中的应用,基底细胞癌（BCC），鳞状细胞癌（SCC），Bowen病（BD）和乳腺外Paget病（EMPD）。研究结果表明，PDD具有扩大临床应用的巨大前景，值得进一步研究探索。
