METHODS: Cases were collected retrospectively from a total of 753 inspiratory and expiratory CT scans performed at our hospital over a 3-year period. Sixteen cases of pure PF-ILD, excluding almost all other diseases, were included. We measured their diseased, normal, and the whole lung volumes manually and evaluated the correlation of their values and their relationship with respiratory function tests (FVC, FVC%-predicted, and DLCO%-predicted).
RESULTS: The relative expansion rate of the diseased lung is no less than that of the normal lung. The \"Expansion volume of total lung\" divided by the \"Expansion volume of normal lung\" was found to be significantly associated with DLCO%-predicted abnormalities (p = 0.0073).
CONCLUSIONS: The diseased lung in PF-ILD retained expansion capacity comparable to the normal lung, suggesting a negative impact on respiratory function.
方法:回顾性收集了在我院进行了3年的共753次吸气和呼气CT扫描的病例。16例纯PF-ILD,排除几乎所有其他疾病,包括在内。我们测量了他们的病情,正常,和手动的整个肺容量,并评估其值的相关性及其与呼吸功能测试的关系(FVC,FVC%-预测,和DLCO%-预测)。
结果:病肺的相对扩张率不低于正常肺。发现“总肺膨胀体积”除以“正常肺膨胀体积”与DLCO%预测异常显着相关(p=0.0073)。
结论:PF-ILD中患病的肺保留了与正常肺相当的扩张能力,提示对呼吸功能有负面影响。