Abstract：
Cilia are fascinating organelles that act as cellular antennae, sensing the cellular environment. Cilia gained significant attention in the late 1990s after their dysfunction was linked to genetic diseases known as ciliopathies. Since then, several breakthrough discoveries have uncovered the mechanisms underlying cilia biogenesis and function. Like most cells in the animal kingdom, neurons also harbor cilia, which are enriched in neuromodulatory receptors. Yet, how neuronal cilia modulate neuronal physiology and animal behavior remains poorly understood. By comparing ciliary biology between the sensory and central nervous systems (CNS), we provide new perspectives on the functions of cilia in brain physiology.
摘要：
纤毛是令人着迷的细胞器，充当细胞触角，感知蜂窝环境。Cilia在1990年代后期获得了极大的关注，因为它们的功能障碍与称为纤毛病的遗传疾病有关。从那以后,一些突破性的发现揭示了纤毛生物发生和功能的潜在机制。像动物界的大多数细胞一样，神经元也有纤毛，它们富含神经调节受体。然而，神经元纤毛如何调节神经元生理和动物行为仍然知之甚少。通过比较感觉和中枢神经系统（CNS）之间的纤毛生物学，我们为纤毛在脑生理中的作用提供了新的观点。
