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Abstract：
BACKGROUND: Birth asphyxia is still one of the primary causes of newborn mortality worldwide. Similarly, the risk of newborn asphyxia in Ethiopia remains unacceptably high. Thus, studies on the incidence and predictors of mortality among newborns admitted with birth asphyxia are crucial to addressing this problem. As a result, the purpose of this study was to assess the incidence and predictors of mortality among neonates admitted with birth asphyxia to the neonatal intensive care units (NICUs) of West Shewa Zone Public Hospitals in Central Ethiopia.
METHODS: An institution-based retrospective cohort study was conducted among 760 asphyxiated neonates admitted to the NICUs of West Shewa Zone Public Hospitals between 30 March 2021 and 30 April 2023. The data were collected using CSEntry and analysed bu using Stata V.17. Bivariate and multivariate Cox proportional hazard regression analyses were carried out, and significant predictors were found using a 95% CI and a p<0.05.
RESULTS: A total of 760 asphyxiated neonates were followed for a total of 6880 neonatal days. At the end of follow-up, 263 (34.6%) of the neonates died (95% CI 31.3% to 38.1%), which resulted in a mortality incidence of 10.6/100 person-days of observation. Chewing khat (adjusted HR, AHR 2.21; 95% CI 1.13 to 4.31), home delivery (AHR 1.45, 95% CI 1.1 to 1.9), lack of antenatal care follow-up (AHR 1.44, 95% CI 1.08 to 1.89), hypothermia (AHR 1.56, 95% CI 1.12 to 2.17), hypoglycaemia (AHR 2.23, 95% CI 1.91 to 2.25) and obstructed labour (AHR 1.4, 95% CI 1.02 to 1.91) were found to be the significant predictors of neonatal mortality among asphyxiated neonates at a p≤0.05.
CONCLUSIONS: The magnitude of neonatal mortality among asphyxiated neonates in the study area was high. Therefore, in order to significantly reduce the risks of birth asphyxia and subsequent newborn death, all interested stakeholders should take these predictors into consideration.
METHODS: An institution-based retrospective cohort study was conducted among 760 asphyxiated neonates admitted to the NICUs of West Shewa Zone Public Hospitals between 30 March 2021 and 30 April 2023. The data were collected using CSEntry and analysed bu using Stata V.17. Bivariate and multivariate Cox proportional hazard regression analyses were carried out, and significant predictors were found using a 95% CI and a p<0.05.
RESULTS: A total of 760 asphyxiated neonates were followed for a total of 6880 neonatal days. At the end of follow-up, 263 (34.6%) of the neonates died (95% CI 31.3% to 38.1%), which resulted in a mortality incidence of 10.6/100 person-days of observation. Chewing khat (adjusted HR, AHR 2.21; 95% CI 1.13 to 4.31), home delivery (AHR 1.45, 95% CI 1.1 to 1.9), lack of antenatal care follow-up (AHR 1.44, 95% CI 1.08 to 1.89), hypothermia (AHR 1.56, 95% CI 1.12 to 2.17), hypoglycaemia (AHR 2.23, 95% CI 1.91 to 2.25) and obstructed labour (AHR 1.4, 95% CI 1.02 to 1.91) were found to be the significant predictors of neonatal mortality among asphyxiated neonates at a p≤0.05.
CONCLUSIONS: The magnitude of neonatal mortality among asphyxiated neonates in the study area was high. Therefore, in order to significantly reduce the risks of birth asphyxia and subsequent newborn death, all interested stakeholders should take these predictors into consideration.
摘要：
背景：出生窒息仍然是全球新生儿死亡的主要原因之一。同样，埃塞俄比亚新生儿窒息的风险仍然高得令人无法接受.因此，对出生窒息新生儿的发病率和死亡率预测因素的研究对于解决这一问题至关重要。因此,本研究的目的是评估埃塞俄比亚中部西舍瓦地区公立医院新生儿重症监护病房(NICU)收治的出生窒息新生儿的发生率和死亡率预测因素.
方法：在2021年3月30日至2023年4月30日期间，对西施瓦地区公立医院NICU收治的760名窒息新生儿进行了一项基于机构的回顾性队列研究。使用CSEntry收集数据，并使用StataV.17进行分析。进行了双变量和多变量Cox比例风险回归分析，使用95%CI和p<0.05发现了显著的预测因子。
结果：共随访760例窒息新生儿共6880天。在后续行动结束时，263例（34.6%）新生儿死亡（95%CI31.3%至38.1%），导致死亡率为10.6/100人-观察日。嚼卡特(调整后的人力资源，AHR2.21；95%CI1.13至4.31)，送货上门（AHR1.45，95%CI1.1至1.9），缺乏产前护理随访(AHR1.44，95%CI1.08至1.89)，体温过低（AHR1.56，95%CI1.12至2.17），在p≤0.05的窒息新生儿中,低血糖(AHR2.23,95%CI1.91~2.25)和难产(AHR1.4,95%CI1.02~1.91)是新生儿死亡率的重要预测因子.
结论：研究区域窒息新生儿死亡率高。因此,为了显着降低出生窒息和随后的新生儿死亡的风险，所有感兴趣的利益相关者都应该考虑这些预测因素。
方法：在2021年3月30日至2023年4月30日期间，对西施瓦地区公立医院NICU收治的760名窒息新生儿进行了一项基于机构的回顾性队列研究。使用CSEntry收集数据，并使用StataV.17进行分析。进行了双变量和多变量Cox比例风险回归分析，使用95%CI和p<0.05发现了显著的预测因子。
结果：共随访760例窒息新生儿共6880天。在后续行动结束时，263例（34.6%）新生儿死亡（95%CI31.3%至38.1%），导致死亡率为10.6/100人-观察日。嚼卡特(调整后的人力资源，AHR2.21；95%CI1.13至4.31)，送货上门（AHR1.45，95%CI1.1至1.9），缺乏产前护理随访(AHR1.44，95%CI1.08至1.89)，体温过低（AHR1.56，95%CI1.12至2.17），在p≤0.05的窒息新生儿中,低血糖(AHR2.23,95%CI1.91~2.25)和难产(AHR1.4,95%CI1.02~1.91)是新生儿死亡率的重要预测因子.
结论：研究区域窒息新生儿死亡率高。因此,为了显着降低出生窒息和随后的新生儿死亡的风险，所有感兴趣的利益相关者都应该考虑这些预测因素。
