Abstract：
Sericin protein possesses excellent biocompatibility, antioxidation, and processability. Nevertheless, manufacturing large quantities of strong and tough pure regenerated sericin materials remains a significant challenge. Herein, we design a lightweight structural sericin film with high ductility by combining radical chain polymerization reaction and liquid-solid phase inversion method. The resulting polyacrylonitrile grafted sericin films exhibit the ability to switch between high strength and high toughness effortlessly, the maximum tensile strength and Young\'s modulus values are 21.92 ± 1.51 MPa and 8.14 ± 0.09 MPa, respectively, while the elongation at break and toughness reaches up to 344.10 ± 35.40 % and 10.84 ± 1.02 MJ·m-3, respectively. Our findings suggest that incorporating sericin into regenerated films contributes to the transformation of their mechanical properties through influencing the entanglement of molecular chains within polymerized solutions. Structural analyses conducted using infrared spectroscopy and X-ray diffraction confirm that sericin modulates the mechanical properties by affecting the transition of condensed matter conformation. This work presents a convenient yet effective strategy for simultaneously addressing the recycling of sericin as well as producing regenerated protein-based films that hold potential applications in biomedical, wearable, or food packaging.
摘要：
丝胶蛋白具有优异的生物相容性,抗氧化，和可加工性。然而，制造大量坚固而坚韧的纯再生丝胶材料仍然是一个重大挑战。在这里，结合自由基链聚合反应和液固相转化方法，设计了一种具有高延展性的轻质丝胶结构膜。所得到的聚丙烯腈接枝丝胶薄膜显示出能够毫不费力地在高强度和高韧性之间切换的能力，最大拉伸强度和杨氏模量值为21.92±1.51MPa和8.14±0.09MPa，分别,断裂伸长率和韧性分别达到344.10±35.40%和10.84±1.02MJ·m-3。我们的发现表明，将丝胶蛋白掺入再生膜中有助于通过影响聚合溶液中分子链的缠结来改变其机械性能。使用红外光谱和X射线衍射进行的结构分析证实，丝胶蛋白通过影响凝聚态构象的转变来调节机械性能。这项工作提出了一种方便而有效的策略，可同时解决丝胶蛋白的回收利用以及生产在生物医学中具有潜在应用的再生蛋白质基薄膜。可穿戴，或食品包装。
