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Abstract：
OBJECTIVE: The aim of this study is to describe the typical microbial spectrum and the influence of distinct vaginal infections on preterm birth in pregnancies affected by cervical incompetence.
METHODS: 327 patients were admitted because of asymptomatic shortening of the cervix in the second and third trimester of pregnancy. Clinical data such as age, cervical length, gestational age at admission and at delivery and vaginal microbiologic findings were collected and analyzed.
RESULTS: The spectrum of germs in the vagina revealed seven different distinct species; the most common bacteria were Ureaplasma spp. and E. coli. In 327 included patients, 217 revealed a bacterial colonization, 110 did not. Most common bacteria in women with preterm birth before 34 weeks were Ureaplasma spp., while E. coli was most common in women undergoing preterm birth after 34 weeks. Nevertheless, the rates of occurrence of these bacterial taxa were not significantly different between who underwent preterm birth to those who did not.
CONCLUSIONS: This study gives an overview over the vaginal bacterial colonization in pregnant women with cervical incompetence. The clinical relevance of vaginal bacterial colonization remains unclear.
METHODS: 327 patients were admitted because of asymptomatic shortening of the cervix in the second and third trimester of pregnancy. Clinical data such as age, cervical length, gestational age at admission and at delivery and vaginal microbiologic findings were collected and analyzed.
RESULTS: The spectrum of germs in the vagina revealed seven different distinct species; the most common bacteria were Ureaplasma spp. and E. coli. In 327 included patients, 217 revealed a bacterial colonization, 110 did not. Most common bacteria in women with preterm birth before 34 weeks were Ureaplasma spp., while E. coli was most common in women undergoing preterm birth after 34 weeks. Nevertheless, the rates of occurrence of these bacterial taxa were not significantly different between who underwent preterm birth to those who did not.
CONCLUSIONS: This study gives an overview over the vaginal bacterial colonization in pregnant women with cervical incompetence. The clinical relevance of vaginal bacterial colonization remains unclear.
摘要：
目的：本研究的目的是描述受宫颈机能不全影响的孕妇中典型的微生物谱和不同的阴道感染对早产的影响。
方法：327例患者因妊娠中期和中期无症状宫颈缩短而入院。临床数据，如年龄，宫颈长度,收集并分析了入院时和分娩时的胎龄以及阴道微生物学结果.
结果：阴道中的细菌谱揭示了7种不同的物种；最常见的细菌是脲原体。和大肠杆菌。在327名患者中，217显示细菌定植，110没有。34周前早产妇女中最常见的细菌是脲原体。,而大肠杆菌在34周后早产的女性中最常见。然而，这些细菌分类群的发生率在早产者和未早产者之间没有显着差异。
结论：本研究概述了宫颈机能不全孕妇的阴道细菌定植。阴道细菌定植的临床意义尚不清楚。
方法：327例患者因妊娠中期和中期无症状宫颈缩短而入院。临床数据，如年龄，宫颈长度,收集并分析了入院时和分娩时的胎龄以及阴道微生物学结果.
结果：阴道中的细菌谱揭示了7种不同的物种；最常见的细菌是脲原体。和大肠杆菌。在327名患者中，217显示细菌定植，110没有。34周前早产妇女中最常见的细菌是脲原体。,而大肠杆菌在34周后早产的女性中最常见。然而，这些细菌分类群的发生率在早产者和未早产者之间没有显着差异。
结论：本研究概述了宫颈机能不全孕妇的阴道细菌定植。阴道细菌定植的临床意义尚不清楚。
