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Abstract：
BACKGROUND: Despite much work having been conducted on magnetic compression anastomosis (MCA) in the digestive tract, there are no reports on the influence of magnetic force on the anastomosis.
OBJECTIVE: To investigate the effect of different magnetic force magnets on the MCA of the digestive tract.
METHODS: Two groups of magnets of the same sizes but different magnetic forces were designed and produced. A total of 24 Sprague-Dawley rats were randomly assigned into two groups (powerful magnet group and common magnet group), with 12 rats in each group. Two types of magnets were used to complete the colonic side-to-side anastomosis of the rats. The operation time and magnet discharge time were recorded. The anastomotic specimens were obtained 4 wk after the operation and then the burst pressure and diameter of the anastomosis were measured, and the anastomosis was observed via the naked eye and subjected to histological examination.
RESULTS: The magnetic forces of the powerful and common magnet groups at zero distance were 8.26 N and 4.10 N, respectively. The colonic side-to-side anastomosis was completed in all 24 rats, and the operation success rate and postoperative survival rate were 100%. No significant difference was noted in the operation time between the two groups. The magnet discharge time of the powerful magnet group was slightly longer than that of the common magnet group, but the difference was not statistically significant (P = 0.513). Furthermore, there was no statistical difference in the burst pressure (P = 0.266) or diameter of magnetic anastomosis (P = 0.095) between the two groups. The gross specimens of the two groups showed good anastomotic healing, and histological observation indicated good mucosal continuity without differences on healing.
CONCLUSIONS: In the rat colonic side-to-side MCA model, both the powerful magnet with 8.26 N and the common magnet with 4.10 N showed no significant impact on the anastomosis establishment process or its effect.
OBJECTIVE: To investigate the effect of different magnetic force magnets on the MCA of the digestive tract.
METHODS: Two groups of magnets of the same sizes but different magnetic forces were designed and produced. A total of 24 Sprague-Dawley rats were randomly assigned into two groups (powerful magnet group and common magnet group), with 12 rats in each group. Two types of magnets were used to complete the colonic side-to-side anastomosis of the rats. The operation time and magnet discharge time were recorded. The anastomotic specimens were obtained 4 wk after the operation and then the burst pressure and diameter of the anastomosis were measured, and the anastomosis was observed via the naked eye and subjected to histological examination.
RESULTS: The magnetic forces of the powerful and common magnet groups at zero distance were 8.26 N and 4.10 N, respectively. The colonic side-to-side anastomosis was completed in all 24 rats, and the operation success rate and postoperative survival rate were 100%. No significant difference was noted in the operation time between the two groups. The magnet discharge time of the powerful magnet group was slightly longer than that of the common magnet group, but the difference was not statistically significant (P = 0.513). Furthermore, there was no statistical difference in the burst pressure (P = 0.266) or diameter of magnetic anastomosis (P = 0.095) between the two groups. The gross specimens of the two groups showed good anastomotic healing, and histological observation indicated good mucosal continuity without differences on healing.
CONCLUSIONS: In the rat colonic side-to-side MCA model, both the powerful magnet with 8.26 N and the common magnet with 4.10 N showed no significant impact on the anastomosis establishment process or its effect.
摘要：
背景：尽管已经对消化道中的磁压缩吻合（MCA）进行了很多工作，没有关于磁力对吻合口影响的报道。
目的：研究不同磁力磁体对消化道MCA的影响。
方法：设计并生产了两组尺寸相同但磁力不同的磁体。将24只Sprague-Dawley大鼠随机分为强磁组和普通磁组,每组12只大鼠。使用两种类型的磁体来完成大鼠的结肠侧对侧吻合。记录操作时间和磁体放电时间。术后4周获得吻合标本，然后测量吻合口的破裂压力和直径，通过肉眼观察吻合并进行组织学检查。
结果：在零距离下，强力和普通磁体组的磁力分别为8.26N和4.10N，分别。结肠侧-侧吻合在所有24只大鼠中完成,手术成功率和术后生存率均为100%。两组手术时间差异无统计学意义。强磁体组的磁体放电时间比普通磁体组略长，但差异无统计学意义(P=0.513)。此外，两组的爆裂压力（P=0.266）和磁吻合直径（P=0.095）无统计学差异。两组标本吻合口愈合良好,组织学观察表明粘膜连续性良好，愈合无差异。
结论：在大鼠结肠侧侧MCA模型中，8.26N的强力磁铁和4.10N的普通磁铁对吻合建立过程或效果均无明显影响。
目的：研究不同磁力磁体对消化道MCA的影响。
方法：设计并生产了两组尺寸相同但磁力不同的磁体。将24只Sprague-Dawley大鼠随机分为强磁组和普通磁组,每组12只大鼠。使用两种类型的磁体来完成大鼠的结肠侧对侧吻合。记录操作时间和磁体放电时间。术后4周获得吻合标本，然后测量吻合口的破裂压力和直径，通过肉眼观察吻合并进行组织学检查。
结果：在零距离下，强力和普通磁体组的磁力分别为8.26N和4.10N，分别。结肠侧-侧吻合在所有24只大鼠中完成,手术成功率和术后生存率均为100%。两组手术时间差异无统计学意义。强磁体组的磁体放电时间比普通磁体组略长，但差异无统计学意义(P=0.513)。此外，两组的爆裂压力（P=0.266）和磁吻合直径（P=0.095）无统计学差异。两组标本吻合口愈合良好,组织学观察表明粘膜连续性良好，愈合无差异。
结论：在大鼠结肠侧侧MCA模型中，8.26N的强力磁铁和4.10N的普通磁铁对吻合建立过程或效果均无明显影响。
