关键词: Iron supplements diabetes ferritin haemoglobin iron deficiency anaemia

来  源:   DOI:10.1097/MS9.0000000000001838   PDF(Pubmed)

Abstract:
Iron deficiency anaemia (IDA) and diabetes mellitus (DM) are most prevalent disease, that diabetic patients are more prone to IDA. Therefore, the main aim of this study was to investigate the relationship between patients with diabetes and IDA in relation to taking iron pills daily and every other day to reduce the effects related to it. Ninety-one participants were enroled and randomly divided into two groups, with a final analysis cohort of 72 patients. The primary focus was on changes in serum Hb and Ferritin levels. The screening phase lasted 24 weeks, leading to 72 eligible participants meeting the criteria for entry into the study. Additionally, the study examined alternations in Hb and Hb A1C levels after treating patients with iron deficiency. The Hb and ferritin level contrasts between groups were not significant (P = 0.096 and P = 0.500, respectively). The relationship between Hb A1C and Hb levels before and after treatment was positive and significant (r 2 = 0.187). The results of the present study show that although the effectiveness of using oral iron supplements did not have a significant difference in terms of increasing haemoglobin and ferritin, the use of oral iron once every other day was more effective than the use of oral iron every day, and also in this study Like other studies, this result concluded that there is a negative correlation between Hb A1C and Hb, and to check the status of Hb A1C in diabetics, the level of Hb should be considered first.
摘要:
缺铁性贫血(IDA)和糖尿病(DM)是最常见的疾病,糖尿病患者更容易患IDA。因此,这项研究的主要目的是调查糖尿病患者与IDA之间的关系,即每天和每隔一天服用铁丸以减少与之相关的影响。91名参与者被招募并随机分为两组,与72例患者的最终分析队列。主要关注血清Hb和铁蛋白水平的变化。筛查阶段持续了24周,导致72名符合条件的参与者符合进入研究的标准。此外,该研究检测了缺铁患者治疗后Hb和HbA1C水平的变化.各组间Hb和铁蛋白水平差异无统计学意义(分别为P=0.096和P=0.500)。治疗前后HbA1C与Hb水平呈正相关(r2=0.187)。本研究的结果表明,尽管使用口服铁补充剂的有效性在增加血红蛋白和铁蛋白方面没有显着差异,每隔一天使用一次口服铁,比每天使用口服铁更有效,在这项研究中,像其他研究一样,此结果得出结论,HbA1C与Hb呈负相关,并检查糖尿病患者的HbA1C状况,首先应考虑Hb水平。
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