关键词: GI bleeding angiodysplasia case report jejunal angiodysplasia upper GI surgery

来  源:   DOI:10.1097/MS9.0000000000001799   PDF(Pubmed)

Abstract:
UNASSIGNED: Angiodysplasia, a rare cause of gastrointestinal (GI) bleeding, presents a spectrum of clinical manifestations from anemia to life-threatening hemorrhage. This case study emphasizes the significance of considering intestinal vascular malformations as a differential diagnosis, especially in the context of chronic anemia and GI bleeding. Jejunal angiodysplasia, though infrequent, poses diagnostic challenges due to the hidden nature of the small bowel in the GI system.
UNASSIGNED: A 23-year-old male presented with acute hematochezia and melena, necessitating prompt intervention. Despite a normal esophagogastroduodenoscopy, colonoscopy was hindered, CT angiography could not be performed due to the patient\'s unstable condition, leading to a planned exploratory laparotomy. Surgical exploration revealed a mucosal vascular lesion in the jejunum, prompting resection, and anastomosis. The patient\'s postoperative course was uneventful, reinforcing the importance of swift diagnosis and intervention.
UNASSIGNED: Angiodysplasia\'s pathogenesis remains unclear, with hypotheses implicating vascular endothelial growth factor and submucosal changes. Challenges in management revolve around lesion localization and stabilizing hemodynamics, necessitating a multidisciplinary approach. While endoscopy is often diagnostic and therapeutic, advanced modalities such as CT angiography may be required. Literature review highlights diverse presentations and successful interventions, including embolization and surgical resection.
UNASSIGNED: Jejunal angiodysplasia demands a comprehensive diagnostic and therapeutic strategy. The presented case underscores the pivotal role of endoscopy, embolization, and surgery in managing this condition. Timely diagnosis and intervention are crucial for mitigating the impact of angiodysplasia, necessitating further research and collaborative efforts for improved management of this rare condition.
摘要:
血管发育不良,胃肠道出血的罕见原因,呈现从贫血到危及生命的出血的一系列临床表现。该病例研究强调了将肠血管畸形作为鉴别诊断的重要性,尤其是在慢性贫血和消化道出血的情况下。空肠血管发育不良,虽然不常见,由于小肠在GI系统中的隐蔽性,提出了诊断挑战。
一名23岁男性出现急性便血和黑便,需要迅速干预。尽管食管胃十二指肠镜检查正常,结肠镜检查受阻,由于患者病情不稳定,无法进行CT血管造影,导致计划中的剖腹探查术。手术探查显示空肠粘膜血管病变,提示切除,和吻合。病人的术后过程是顺利的,加强快速诊断和干预的重要性。
血管增生的发病机制尚不清楚,假设涉及血管内皮生长因子和粘膜下变化。管理中的挑战围绕病变定位和稳定血流动力学,需要多学科方法。虽然内窥镜检查通常是诊断和治疗,可能需要先进的方式,如CT血管造影。文献综述强调了不同的演讲和成功的干预措施,包括栓塞和手术切除。
空肠血管发育不良需要全面的诊断和治疗策略。所呈现的病例强调了内窥镜检查的关键作用,栓塞,和手术来控制这种情况。及时诊断和干预对于减轻血管增生的影响至关重要。需要进一步的研究和合作努力来改善这种罕见疾病的管理。
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