PDF(Pubmed)
Abstract：
Dermatophytes, fungi specialized in keratin degradation, are key agents in skin infections, commonly referred to as tineas. Tinea manuum, affecting the hands, typically presents in noninflammatory or inflammatory forms, with ulcerative manifestations rarely reported. Nannizzia gypsea, a relatively uncommon cause of tineas, exhibits variable prevalence influenced by geographic factors. This study investigates a case of Ulcerative Unilateral Tinea Manuum caused by N. gypsea, aiming to explore the differential diagnosis, pathogenesis, and management. A 23-year-old female from the Yucatan Peninsula presented with an ulcerated lesion on her left hand. Initially suspected as Leishmaniasis, subsequent examination revealed tinea manuum. The study discusses differential diagnoses, highlighting the rarity of ulcerative presentations in dermatophytosis, and explores potential pathogenic mechanisms. This case underscores the importance of considering dermatophytes in ulcerative skin lesions and suggests a comprehensive diagnostic approach, particularly in endemic regions.
摘要：
皮肤癣菌,专门研究角蛋白降解的真菌，是皮肤感染的关键药物，通常被称为tineas。手癣,影响手，通常表现为非炎症或炎症形式，很少报道溃疡性表现。Nannizziagypsea,一个相对不常见的原因，表现出受地理因素影响的不同患病率。本研究调查了一例由埃及奈瑟菌引起的溃疡性单侧足癣，旨在探索鉴别诊断，发病机制，和管理。一名来自尤卡坦半岛的23岁女性左手出现溃疡病变。最初怀疑是利什曼病，随后的检查显示手癣。这项研究讨论了鉴别诊断，强调皮肤癣菌病中溃疡性表现的罕见性，并探索潜在的致病机制。该病例强调了在溃疡性皮肤病变中考虑皮肤癣菌的重要性，并提出了全面的诊断方法。特别是在流行地区。
