PDF(Pubmed)
Abstract：
Brugada syndrome is an autosomal dominant channelopathy that usually affects healthy young males without apparent structural heart disease. It is associated with a spectrum of variable and dynamic clinical manifestations, high risk of life-threatening ventricular arrhythmias, and sudden cardiac death. Our patient demonstrated transient and dynamic EKG changes of both type 1 (coved) and type 2 (saddleback) ST elevation, suggestive of the Brugada pattern that was associated with physical chest trauma and stressful situations. While common triggers like fever and certain drugs are well-recognized, this case illustrates the potential for physical stress and trauma to unmask or aggravate Brugada syndrome, albeit without definitive evidence for a causal link. Ultimately, this report underscores the importance of considering a broad differential diagnosis, including Brugada syndrome, in patients presenting with unexplained syncope or characteristic EKG changes, even when traditional triggers are absent.
摘要：
Brugada综合征是一种常染色体显性通道病，通常影响健康的年轻男性，而没有明显的结构性心脏病。它与一系列可变和动态的临床表现有关，危及生命的室性心律失常的风险很高,和心源性猝死.我们的患者表现出1型（闭合）和2型（鞍背）ST抬高的瞬时和动态EKG变化，暗示与身体胸部创伤和压力情况相关的Brugada模式。虽然常见的诱因如发烧和某些药物是公认的，这个案例说明了身体压力和创伤暴露或加重Brugada综合征的可能性，尽管没有明确的因果关系证据。最终,这份报告强调了考虑广泛鉴别诊断的重要性，包括Brugada综合征,出现不明原因晕厥或特征性心电图改变的患者，即使没有传统的触发器。
