PDF(Pubmed)
Abstract：
UNASSIGNED: To develop a model for the accurate prediction of calculous obstructive pyonephrosis prior to percutaneous nephrolithotomy (PNL), leading to early local anaesthesia microchannel nephrostomy for drainage of pyonephrosis.
UNASSIGNED: By comparing the differences in baseline clinical indicators between the pyonephrosis group and nonpyonephrosis groups, independent risk factors were screened out, and a diagnostic alignment diagram model for predicting calculus obstructive pyonephrosis before PNL was established.
UNASSIGNED: Multivariate regression analysis showed that preoperative blood neutrophil count (Neu), serum creatinine level (Scr), serum albumin level (Alb), urine nitrite (UN), hydronephrosis density (HD) and fever history within one month (HFWOM) were independent risk factors for calculous obstructive pyonephrosis. The AUC value of the receiver operating characteristic (ROC) curve was 0.929. The calibration curves showed that the predictive model was well corrected and that the predictive model had strong consistency. Decision analysis curves showed good clinical efficacy of the model.
UNASSIGNED: The alignment diagram model accurately predicts patients with preoperative calculous obstructive pyonephrosis in the PNL and provides an evidence-based basis for early renal microchannel nephrostomy.
UNASSIGNED: By comparing the differences in baseline clinical indicators between the pyonephrosis group and nonpyonephrosis groups, independent risk factors were screened out, and a diagnostic alignment diagram model for predicting calculus obstructive pyonephrosis before PNL was established.
UNASSIGNED: Multivariate regression analysis showed that preoperative blood neutrophil count (Neu), serum creatinine level (Scr), serum albumin level (Alb), urine nitrite (UN), hydronephrosis density (HD) and fever history within one month (HFWOM) were independent risk factors for calculous obstructive pyonephrosis. The AUC value of the receiver operating characteristic (ROC) curve was 0.929. The calibration curves showed that the predictive model was well corrected and that the predictive model had strong consistency. Decision analysis curves showed good clinical efficacy of the model.
UNASSIGNED: The alignment diagram model accurately predicts patients with preoperative calculous obstructive pyonephrosis in the PNL and provides an evidence-based basis for early renal microchannel nephrostomy.
摘要：
■为了开发一种在经皮肾镜取石术（PNL）之前准确预测结石性梗阻性脓肾的模型，导致早期局部麻醉微通道肾造口术引流脓肾。
■通过比较脓肾组与非脓肾组的基线临床指标的差异，筛选出独立危险因素,建立PNL前预测结石梗阻性脓肾的诊断对齐图模型。
■多因素回归分析显示术前中性粒细胞计数(Neu),血清肌酐水平（Scr），血清白蛋白水平（Alb），尿亚硝酸盐（UN），肾积水密度(HD)和1个月内有发热史(HFWOM)是结石梗阻性肾积脓的独立危险因素。受试者工作特征(ROC)曲线的AUC值为0.929。校正曲线表明,预测模型校正效果良好,预测模型具有较强的一致性。决策分析曲线显示模型具有良好的临床疗效。
■对齐图模型可以准确预测PNL术前结石性梗阻性脓肾患者，为早期肾微通道肾造口术提供循证依据。
■通过比较脓肾组与非脓肾组的基线临床指标的差异，筛选出独立危险因素,建立PNL前预测结石梗阻性脓肾的诊断对齐图模型。
■多因素回归分析显示术前中性粒细胞计数(Neu),血清肌酐水平（Scr），血清白蛋白水平（Alb），尿亚硝酸盐（UN），肾积水密度(HD)和1个月内有发热史(HFWOM)是结石梗阻性肾积脓的独立危险因素。受试者工作特征(ROC)曲线的AUC值为0.929。校正曲线表明,预测模型校正效果良好,预测模型具有较强的一致性。决策分析曲线显示模型具有良好的临床疗效。
■对齐图模型可以准确预测PNL术前结石性梗阻性脓肾患者，为早期肾微通道肾造口术提供循证依据。
