PDF(Pubmed)
Abstract：
Bersama (Melianthaceae) has been used in traditional medicine for a wide range of ailments, including blood purifier, immune booster, psychotropic medication, and treatment for malaria, hepatitis, infertility, diabetes, impotency, meningitis, and stroke. This review gathers fragmented information from the literature on ethnomedicinal applications, phytochemistry, pharmacology, and toxicology of the Bersama genus. It also explores the therapeutic potential of the Bersama genus in ethnophytopharmacology, allowing for further investigation. All the available information published in the English language on Bersama genus was compiled from electronic databases such as Academic Journals, Ethnobotany, Google Scholar, PubMed, Science Direct, Web of Science, and library search using the following keywords: \"Bersama genus,\" \"traditional use,\" \"phytochemistry,\" \"pharmacological effects,\" and \"toxicology\". The ethnomedical applications of the Bersama genus have been recorded, and it has been used traditionally for more than 30 different types of ailments. Thus far, more than 50 compounds have been isolated from the genus. Cardiac glycosides and terpenoids are the main compounds isolated from the Bersama genus. Different plant parts of Bersama genus extracts demonstrated a wide range of pharmacological properties, including antioxidant, antimalarial, antidiabetic, antiviral, anti-inflammatory, and cytotoxic activity. Exemplary drug leads from the genus include mangiferin and quercetin-3-O-arabinopyranoside, both of which have antioxidant activities. Bersama genus has long been used to cure a wide range of ailments. Bersama genus extracts and phytochemicals have been found to have promising pharmacological activities. Further study on promising crude extracts and compounds is required to develop innovative therapeutic candidates.
摘要：
Bersama（Melianthaceae）已用于传统医学中的各种疾病，包括血液净化器,免疫增强剂,精神药物,和治疗疟疾，肝炎，不孕症,糖尿病,阳痿,脑膜炎,和中风。这篇综述从关于种族医学应用的文献中收集了零散的信息，植物化学,药理学,和Bersama属的毒理学。它还探讨了Bersama属在人质病学中的治疗潜力，允许进一步调查。所有可用的信息发表在英语中的Bersama属的电子数据库，如学术期刊，民族植物学,谷歌学者，PubMed,科学直接，WebofScience,并使用以下关键字进行图书馆搜索：“Bersama属，传统使用，植物化学，“\”药理作用，\"和\"毒理学\"。已经记录了Bersama属的生物医学应用，传统上，它已被用于30多种不同类型的疾病。到目前为止,从该属中分离出50多种化合物。从Bersama属中分离出的主要化合物是强心苷和萜类化合物。Bersama属提取物的不同植物部分表现出广泛的药理特性，包括抗氧化剂，抗疟药,抗糖尿病药,抗病毒，抗炎,和细胞毒活性。该属的示例性药物线索包括芒果苷和槲皮素-3-O-阿拉伯吡喃，两者都具有抗氧化活性。Bersama属长期以来一直用于治疗多种疾病。已发现Bersama属提取物和植物化学物质具有有希望的药理活性。需要对有前途的粗提物和化合物进行进一步研究，以开发创新的治疗候选物。
