关键词: abdominal pain anterior cutaneous nerve entrapment syndrome children lidocaine patch local neuropathy

Mesh : Humans Lidocaine / administration & dosage therapeutic use Retrospective Studies Male Female Adolescent Anesthetics, Local / administration & dosage therapeutic use Child Nerve Compression Syndromes / surgery drug therapy Transdermal Patch Treatment Outcome Abdominal Pain / drug therapy

来  源:   DOI:10.1111/pan.14890

Abstract:
Chronic abdominal pain in children is occasionally caused by anterior cutaneous nerve entrapment syndrome (ACNES). Diagnosing and treating this typical peripheral abdominal wall neuropathy is challenging. Management usually starts with minimally invasive tender point injections. Nevertheless, these injections can be burdensome and might even be refused by children or their parents. However, a surgical neurectomy is far more invasive. Treatment with a Lidocaine 5% medicated patch is successfully used in a variety of peripheral neuropathies.
This single center retrospective case series aimed to evaluate the effectiveness and tolerability of lidocaine patches in children with ACNES.
Children aged under 18 diagnosed with ACNES who were treated with a 10 day lidocaine patch treatment between December 2021 and December 2022 were studied. Patient record files were used to collect treatment outcomes including pain reduction based on NRS and complications.
Twelve of sixteen children (mean age 13 years; F:M ratio 3:1) diagnosed with ACNES started the lidocaine patch treatment. Two patients achieved a pain free status and remained pain free during a 4 and 7 months follow-up. A third child reported a lasting pain reduction, but discontinued treatment due to a temporary local skin rash. Five additional patients reported pain reduction only during application of the patch. The remaining four children experienced no pain relief. No adverse effects were reported.
Lidocaine patches provides pain relief in a substantial portion of children with ACNES.
摘要:
背景:儿童慢性腹痛偶尔由前皮神经卡压综合征(ACNES)引起。诊断和治疗这种典型的周围腹壁神经病具有挑战性。管理通常从微创压痛点注射开始。然而,这些注射可能是繁重的,甚至可能被孩子或他们的父母拒绝。然而,手术神经切除术更具侵入性。用5%利多卡因药物贴剂治疗已成功用于多种周围神经病变。
目的:此单中心回顾性病例系列旨在评估利多卡因贴剂在ACNES患儿中的有效性和耐受性。
方法:研究了在2021年12月至2022年12月期间接受10天利多卡因贴片治疗的18岁以下被诊断为ACNES的儿童。患者记录文件用于收集治疗结果,包括基于NRS和并发症的疼痛减轻。
结果:诊断为ACNES的16名儿童中有12名(平均年龄13岁;F:M比3:1)开始使用利多卡因贴片治疗。两名患者获得了无痛状态,并在4和7个月的随访中保持无痛状态。第三个孩子报告说疼痛持续减轻,但由于暂时性局部皮疹而停止治疗。另外五名患者报告仅在贴剂应用期间疼痛减轻。其余四个孩子没有缓解疼痛。无不良反应报告。
结论:利多卡因贴剂可缓解大部分ACNES患儿的疼痛。
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