PDF(Pubmed)
Abstract：
UNASSIGNED: Non-gestational choriocarcinoma, also known as primary choriocarcinoma, is extremely rare in men, manifesting with specific signs such as breast feminization, testicular atrophy, and loss of libido. The presentation typically includes elevated serum β-hCG levels, widespread metastatic disease, and a rapid progression of the condition.
UNASSIGNED: We present a rare case of a 41-year-old man diagnosed with choriocarcinoma, exhibiting a unique combination of multiple metastases, including lung, brain, bone, and retroperitoneal lymph node metastases, as confirmed by 18F-FDG PET/CT imaging. The patient was treated with aggressive chemotherapy and pembrolizumab, and the prognosis remained poor. The patient\'s overall survival was a mere 5 months following diagnosis.
UNASSIGNED: Non-gestational choriocarcinoma represents a rare entity in clinical practice and should be considered in young men presenting with gynaecomastia and elevated β-hCG levels alongside normal gonads. Thus, we advocate for a more comprehensive inquiry into medical history and a systematic examination. The 18F-FDG PET/CT examination not only visually delineates the lesion\'s location and extent but also serves as a cornerstone for clinical tumor staging, providing valuable support for treatment monitoring and subsequent follow-up.
UNASSIGNED: We present a rare case of a 41-year-old man diagnosed with choriocarcinoma, exhibiting a unique combination of multiple metastases, including lung, brain, bone, and retroperitoneal lymph node metastases, as confirmed by 18F-FDG PET/CT imaging. The patient was treated with aggressive chemotherapy and pembrolizumab, and the prognosis remained poor. The patient\'s overall survival was a mere 5 months following diagnosis.
UNASSIGNED: Non-gestational choriocarcinoma represents a rare entity in clinical practice and should be considered in young men presenting with gynaecomastia and elevated β-hCG levels alongside normal gonads. Thus, we advocate for a more comprehensive inquiry into medical history and a systematic examination. The 18F-FDG PET/CT examination not only visually delineates the lesion\'s location and extent but also serves as a cornerstone for clinical tumor staging, providing valuable support for treatment monitoring and subsequent follow-up.
摘要：
■非妊娠绒毛膜癌，也被称为原发性绒毛膜癌，在男性中极为罕见,表现为特定的体征，如乳房女性化，睾丸萎缩,和性欲的丧失。表现通常包括血清β-hCG水平升高，广泛的转移性疾病，和病情的快速发展。
我们介绍了一例罕见的41岁男性绒毛膜癌，表现出独特的多发性转移组合，包括肺,大脑,骨头,和腹膜后淋巴结转移,18F-FDGPET/CT显像证实。该患者接受了积极的化疗和pembrolizumab，预后仍然很差。患者的总生存期仅为诊断后5个月。
■非妊娠绒毛膜癌在临床实践中是一种罕见的实体，应在表现为妇科乳房发育和正常性腺的β-hCG水平升高的年轻男性中考虑。因此，我们主张对病史进行更全面的调查和系统的检查。18F-FDGPET/CT检查不仅可以直观地描绘病变的位置和范围，而且可以作为临床肿瘤分期的基石。为治疗监测和后续随访提供有价值的支持。
我们介绍了一例罕见的41岁男性绒毛膜癌，表现出独特的多发性转移组合，包括肺,大脑,骨头,和腹膜后淋巴结转移,18F-FDGPET/CT显像证实。该患者接受了积极的化疗和pembrolizumab，预后仍然很差。患者的总生存期仅为诊断后5个月。
■非妊娠绒毛膜癌在临床实践中是一种罕见的实体，应在表现为妇科乳房发育和正常性腺的β-hCG水平升高的年轻男性中考虑。因此，我们主张对病史进行更全面的调查和系统的检查。18F-FDGPET/CT检查不仅可以直观地描绘病变的位置和范围，而且可以作为临床肿瘤分期的基石。为治疗监测和后续随访提供有价值的支持。
