PDF(Pubmed)
Abstract：
UNASSIGNED: To assess patient comfort, wound healing, and scarring at the 6-month follow-up of split-skin graft donor sites treated with Ba-Hao burn ointment (BHBO) gauze, a compound preparation of traditional Chinese medicine since 1970s, compared with petrolatum gauze.
UNASSIGNED: Thirty patients admitted to the Department of Burns of the First Affiliated Hospital of Anhui Medical University between September 2021 and September 2022 participated in this randomized, prospective, self-control clinical study. After harvesting the split skin, donor sites were divided into two parts along the midline. BHBO gauze was applied to half of the donor wounds, and petrolatum gauze was applied to the other half. The wound healing time, pain scores on the postoperative Days 3, 6, and 9, and Vancouver Scar Scale (VSS) score at the 6-month follow-up were assessed.
UNASSIGNED: The wound healing time was significantly shorter in the BHBO group than in the control group (10.07 ± 1.48 days vs. 11.50 ± 1.74 days, p < 0.001). On postoperative Days 3 and 6, the pain scores quantified by visual analog scores were significantly lower in the BHBO group than in the control group (5.33 ± 1.54 and 4.17 ± 1.51, respectively vs. 7.57 ± 1.41 and 5.20 ± 1.47, respectively). The difference in the visual analog scale score on postoperative Day 9 between the groups was not significant (p > 0.05). Microbiological assessment revealed the absence of bacterial contamination in both groups. At the 6-month follow up, the VSS score was significantly lower in the BHBO group (6.67 ± 1.92) than in the control group (9.57 ± 1.55).
UNASSIGNED: BHBO resulted in faster donor-site healing, reduced postoperative pain, and improved scar quality at the 6-month follow-up than petrolatum gauze alone.
UNASSIGNED: Thirty patients admitted to the Department of Burns of the First Affiliated Hospital of Anhui Medical University between September 2021 and September 2022 participated in this randomized, prospective, self-control clinical study. After harvesting the split skin, donor sites were divided into two parts along the midline. BHBO gauze was applied to half of the donor wounds, and petrolatum gauze was applied to the other half. The wound healing time, pain scores on the postoperative Days 3, 6, and 9, and Vancouver Scar Scale (VSS) score at the 6-month follow-up were assessed.
UNASSIGNED: The wound healing time was significantly shorter in the BHBO group than in the control group (10.07 ± 1.48 days vs. 11.50 ± 1.74 days, p < 0.001). On postoperative Days 3 and 6, the pain scores quantified by visual analog scores were significantly lower in the BHBO group than in the control group (5.33 ± 1.54 and 4.17 ± 1.51, respectively vs. 7.57 ± 1.41 and 5.20 ± 1.47, respectively). The difference in the visual analog scale score on postoperative Day 9 between the groups was not significant (p > 0.05). Microbiological assessment revealed the absence of bacterial contamination in both groups. At the 6-month follow up, the VSS score was significantly lower in the BHBO group (6.67 ± 1.92) than in the control group (9.57 ± 1.55).
UNASSIGNED: BHBO resulted in faster donor-site healing, reduced postoperative pain, and improved scar quality at the 6-month follow-up than petrolatum gauze alone.
摘要：
■为了评估患者的舒适度，伤口愈合，在用Ba-Hao烧伤软膏（BHBO）纱布治疗的裂片移植供体部位的6个月随访中，自1970年代以来的中药复方制剂，与凡士林纱布相比。
■在2021年9月至2022年9月期间，安徽医科大学第一附属医院烧伤科收治的30名患者参与了这项随机研究。prospective,自我对照临床研究。收获分裂的皮肤后，捐赠地点沿中线分为两部分。将BHBO纱布涂在一半的供体伤口上，另一半上涂了凡士林纱布。伤口愈合的时间，评估术后第3,6和9天的疼痛评分以及6个月随访时的温哥华疤痕量表(VSS)评分.
■BHBO组的伤口愈合时间明显短于对照组（10.07±1.48天vs.11.50±1.74天，p<0.001)。在术后第3天和第6天，BHBO组通过视觉模拟评分量化的疼痛评分显着低于对照组（分别为5.33±1.54和4.17±1.51。分别为7.57±1.41和5.20±1.47）。术后第9天视觉模拟量表评分组间差异无统计学意义(p>0.05)。微生物学评估显示两组均无细菌污染。在6个月的随访中，BHBO组的VSS评分（6.67±1.92）明显低于对照组（9.57±1.55）。
■BHBO导致更快的供体部位愈合，减少术后疼痛，在6个月的随访中，疤痕质量比单独使用凡士林纱布改善。
■在2021年9月至2022年9月期间，安徽医科大学第一附属医院烧伤科收治的30名患者参与了这项随机研究。prospective,自我对照临床研究。收获分裂的皮肤后，捐赠地点沿中线分为两部分。将BHBO纱布涂在一半的供体伤口上，另一半上涂了凡士林纱布。伤口愈合的时间，评估术后第3,6和9天的疼痛评分以及6个月随访时的温哥华疤痕量表(VSS)评分.
■BHBO组的伤口愈合时间明显短于对照组（10.07±1.48天vs.11.50±1.74天，p<0.001)。在术后第3天和第6天，BHBO组通过视觉模拟评分量化的疼痛评分显着低于对照组（分别为5.33±1.54和4.17±1.51。分别为7.57±1.41和5.20±1.47）。术后第9天视觉模拟量表评分组间差异无统计学意义(p>0.05)。微生物学评估显示两组均无细菌污染。在6个月的随访中，BHBO组的VSS评分（6.67±1.92）明显低于对照组（9.57±1.55）。
■BHBO导致更快的供体部位愈合，减少术后疼痛，在6个月的随访中，疤痕质量比单独使用凡士林纱布改善。
