PDF(Pubmed)
Abstract：
UNASSIGNED: Many studies have associated male androgenetic alopecia with the risk of cardiovascular disorders but very few studies have addressed this association in women with FPHL.
UNASSIGNED: This was a cross-sectional hospital-based study in which a total of 50 women (18-45 years) were recruited. The objective was to measure carotid intima-media thickness (CIMT) by doppler ultrasound, Body mass index (BMI), waist circumference, lipid profile, fasting blood sugar (FBS), insulin, testosterone, Sex hormone binding globulin (SHBG), hs-CRP, ESR and fibrinogen, in pre-menopausal women having FPHL and to correlate these parameters with severity of FPHL. The prevalence of Metabolic syndrome (MetS) and Insulin resistance were evaluated.
UNASSIGNED: Metabolic syndrome and insulin resistance were found in 12 (24%) and 17 (34%) cases respectively. Hypercholesterolemia, elevated LDL levels and hypertriglyceridemia, low HDL levels and hyperinsulinemia were found in 11 (22%), 31 (62%), 9 (18%), 17 (34%) and 7 (14%) cases respectively. 8 (16%) cases were diabetics. Elevated ESR, increased fibrinogen levels and elevated hs-CRP were found in 43 (86%), 10 (20%) and 21 (42%) cases respectively. CIMT was found to be within its normal range. Correlation of CIMT, anthropometric indices (BMI and WC), biochemical markers (serum cholesterol, triglycerides, FBS, and fibrinogen), and presence of metabolic syndrome with severity of FPHL in terms of Ludwig grade was found to be statistically significant.
UNASSIGNED: The determination of metabolic syndrome, insulin resistance and acute phase reactants such as hs-CRP and fibrinogen may be useful screening methods to detect increased cardiovascular risk in women with FPHL.
UNASSIGNED: This was a cross-sectional hospital-based study in which a total of 50 women (18-45 years) were recruited. The objective was to measure carotid intima-media thickness (CIMT) by doppler ultrasound, Body mass index (BMI), waist circumference, lipid profile, fasting blood sugar (FBS), insulin, testosterone, Sex hormone binding globulin (SHBG), hs-CRP, ESR and fibrinogen, in pre-menopausal women having FPHL and to correlate these parameters with severity of FPHL. The prevalence of Metabolic syndrome (MetS) and Insulin resistance were evaluated.
UNASSIGNED: Metabolic syndrome and insulin resistance were found in 12 (24%) and 17 (34%) cases respectively. Hypercholesterolemia, elevated LDL levels and hypertriglyceridemia, low HDL levels and hyperinsulinemia were found in 11 (22%), 31 (62%), 9 (18%), 17 (34%) and 7 (14%) cases respectively. 8 (16%) cases were diabetics. Elevated ESR, increased fibrinogen levels and elevated hs-CRP were found in 43 (86%), 10 (20%) and 21 (42%) cases respectively. CIMT was found to be within its normal range. Correlation of CIMT, anthropometric indices (BMI and WC), biochemical markers (serum cholesterol, triglycerides, FBS, and fibrinogen), and presence of metabolic syndrome with severity of FPHL in terms of Ludwig grade was found to be statistically significant.
UNASSIGNED: The determination of metabolic syndrome, insulin resistance and acute phase reactants such as hs-CRP and fibrinogen may be useful screening methods to detect increased cardiovascular risk in women with FPHL.
摘要：
许多研究将男性雄激素性脱发与心血管疾病的风险联系起来，但很少有研究解决女性FPHL的这种联系。
这是一项基于医院的横断面研究，共招募了50名女性（18-45岁）。目的是通过多普勒超声测量颈动脉内中膜厚度（CIMT），身体质量指数(BMI),腰围,血脂谱,空腹血糖（FBS），胰岛素，睾丸激素，性激素结合球蛋白(SHBG),hs-CRP,ESR和纤维蛋白原，在绝经前患有FPHL的妇女中，并将这些参数与FPHL的严重程度相关联。评估代谢综合征（MetS）和胰岛素抵抗的患病率。
■分别在12例（24％）和17例（34％）中发现了代谢综合征和胰岛素抵抗。高胆固醇血症,LDL水平升高和高甘油三酯血症，低HDL水平和高胰岛素血症见于11例（22%），31（62%），9（18%），分别为17例(34%)和7例(14%)。8例(16%)为糖尿病患者。ESR升高,纤维蛋白原水平升高和hs-CRP升高在43（86％），10例(20%)和21例(42%)。发现CIMT在其正常范围内。CIMT的相关性，人体测量指数（BMI和WC），生化标志物(血清胆固醇，甘油三酯，FBS,和纤维蛋白原），根据Ludwig分级，代谢综合征的存在与FPHL的严重程度有统计学意义。
■代谢综合征的测定，胰岛素抵抗和hs-CRP和纤维蛋白原等急性期反应物可能是检测FPHL女性心血管风险增加的有用筛查方法.
这是一项基于医院的横断面研究，共招募了50名女性（18-45岁）。目的是通过多普勒超声测量颈动脉内中膜厚度（CIMT），身体质量指数(BMI),腰围,血脂谱,空腹血糖（FBS），胰岛素，睾丸激素，性激素结合球蛋白(SHBG),hs-CRP,ESR和纤维蛋白原，在绝经前患有FPHL的妇女中，并将这些参数与FPHL的严重程度相关联。评估代谢综合征（MetS）和胰岛素抵抗的患病率。
■分别在12例（24％）和17例（34％）中发现了代谢综合征和胰岛素抵抗。高胆固醇血症,LDL水平升高和高甘油三酯血症，低HDL水平和高胰岛素血症见于11例（22%），31（62%），9（18%），分别为17例(34%)和7例(14%)。8例(16%)为糖尿病患者。ESR升高,纤维蛋白原水平升高和hs-CRP升高在43（86％），10例(20%)和21例(42%)。发现CIMT在其正常范围内。CIMT的相关性，人体测量指数（BMI和WC），生化标志物(血清胆固醇，甘油三酯，FBS,和纤维蛋白原），根据Ludwig分级，代谢综合征的存在与FPHL的严重程度有统计学意义。
■代谢综合征的测定，胰岛素抵抗和hs-CRP和纤维蛋白原等急性期反应物可能是检测FPHL女性心血管风险增加的有用筛查方法.
