关键词: gynecology and obstetrics medical management methotrexate ectopic mifepristone scar ectopic pregnancy

来  源:   DOI:10.7759/cureus.55481   PDF(Pubmed)

Abstract:
One of the rarest types of ectopic pregnancy, with an incidence of 1:1,800, is cesarean scar ectopic pregnancy. Here, we report the case of a 28-year-old woman who had undergone two previous cesarean sections. She arrived at our labor room with per vaginal spotting and abdominal pain with an ultrasound that revealed a cesarean scar ectopic pregnancy. The initial beta-human chorionic gonadotropin (β-hCG) value upon admission was 27,133 mIU/mL. Her ultrasound findings were confirmed with magnetic resonance imaging. Opting for combined medical management, we successfully treated her using systemic methotrexate and mifepristone, avoiding surgical intervention despite high β-hCG values. There is currently no established standardized treatment for cesarean scar ectopic pregnancies, and we feel that treatment must be tailored to every patient\'s individual needs. Our experience suggests that combining mifepristone and systemic methotrexate can be an effective approach with better curative effects, emphasizing the need for further research.
摘要:
一种最罕见的异位妊娠,发病率为1:1800,是剖宫产瘢痕异位妊娠。这里,我们报道了1例28岁女性,该女性曾接受过两次剖宫产手术.她来到我们的分娩室,每次阴道斑点和腹痛,超声检查显示剖宫产疤痕异位妊娠。入院时最初的β-人绒毛膜促性腺激素(β-hCG)值为27,133mIU/mL。磁共振成像证实了她的超声检查结果。选择合并医疗管理,我们用氨甲蝶呤和米非司酮成功治疗了她,尽管β-hCG值较高,但仍避免手术干预。目前尚无确定的剖宫产瘢痕异位妊娠的标准化治疗方法,我们认为治疗必须针对每个患者的个人需求。我们的经验表明,米非司酮和全身性甲氨蝶呤联合治疗可能是一种疗效更好的有效方法。强调需要进一步研究。
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