关键词: early-onset preeclampsia fetal loss hypertensive disorders in pregnancy (hdp) intrauterine fetal demise posterior reversible encephalopathy syndrome (pres) preeclampsia complications preeclampsia with severe features

来  源:   DOI:10.7759/cureus.55490   PDF(Pubmed)

Abstract:
Posterior reversible encephalopathy syndrome (PRES) can be defined as a clinical syndrome of headache, seizures, visual disturbance, altered mental status, and characteristic magnetic resonance imaging (MRI) findings of vasogenic edema in the posterior subcortical parietal-occipital white matter. There are numerous potential inciting factors, including immunosuppression, renal disease, malignancy, cytotoxic medications, hypertension, preeclampsia, and eclampsia. In this paper, we present the case of a 21-year-old female at 19 weeks gestation presenting with symptoms consistent with preeclampsia with severe features and PRES. She was transferred to our facility after initial stabilization. She had an atypical course of preeclampsia prior to 20 weeks gestation, PRES lacking seizure activity, and ultimately her case resulted in intrauterine fetal demise (IUFD) at 20 weeks and six days gestation. As indicated by its name, PRES is considered a fully reversible syndrome, and the patient recovered after stabilization of her hypertensive disorder and delivery of the fetus. This case illustrates the importance of prompt recognition and treatment of hypertensive disorders in pregnant patients and the possibility of complications that can result in significant morbidity and mortality for both the mother and fetus.
摘要:
可逆性后部脑病综合征(PRES)可以定义为头痛的临床综合征,癫痫发作,视觉障碍,精神状态改变,和特征性磁共振成像(MRI)发现后皮质下顶叶-枕骨白质血管源性水肿。有许多潜在的煽动因素,包括免疫抑制,肾脏疾病,恶性肿瘤,细胞毒性药物,高血压,先兆子痫,和子痫。在本文中,我们介绍了1例21岁女性,在妊娠19周时,其症状与具有严重特征和PRES的先兆子痫一致.她在初步稳定后被转移到我们的设施。她在妊娠20周前有不典型的先兆子痫病程,PRES缺乏癫痫发作活动,最终她的病例导致胎儿宫内死亡(IUFD)在妊娠20周和6天。正如它的名字所示,PRES被认为是一种完全可逆的综合征,患者在高血压疾病稳定和胎儿分娩后康复。这种情况说明了迅速识别和治疗妊娠患者高血压疾病的重要性,以及可能导致母亲和胎儿的大量发病率和死亡率的并发症的可能性。
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