关键词: adrenal pheochromocytoma adrenal surgery endocrine neoplasms hypertension and pheochromocytoma neuroendocrine neoplasm

来  源:   DOI:10.7759/cureus.55504   PDF(Pubmed)

Abstract:
Pheochromocytomas are neuroendocrine tumors that produce, store, and secrete catecholamines. They are found in the chromaffin tissue of the adrenal medulla and manifest clinical symptoms by producing an excessive amount of one or more catecholamines, such as dopamine, adrenaline, and noradrenaline, as well as their inactive metabolites, such as metanephrine, normetanephrine, and 3-methoxytyramine. This paper is the case report of a 53-year-old male patient with diabetes and hypertension who has been experiencing symptoms such as night sweats, frequent colds, weight loss, reduced appetite, and generalized anxiety. The patient presented with pelvic pain and sought medical attention, leading to an abdominal MRI scan that revealed a right adrenal mass. The patient\'s plasma metanephrine levels were found to be four-fold higher than the normal range. A contrast CT scan of the abdomen and pelvis revealed a right adrenal gland with increased dimensions and well-defined edges. A diagnosis of right adrenal pheochromocytoma was made. The patient underwent a right laparoscopic adrenalectomy, which resulted in a reduction in metanephrine levels and normal blood pressure readings. The patient presented a favorable clinical evolution in the post-surgical period, for which it was decided to be discharged home.
摘要:
嗜铬细胞瘤是神经内分泌肿瘤,store,分泌儿茶酚胺.它们存在于肾上腺髓质的嗜铬细胞组织中,并通过产生过量的一种或多种儿茶酚胺来表现临床症状,比如多巴胺,肾上腺素,和去甲肾上腺素,以及它们的无活性代谢物,比如间肾上腺素,去甲肾上腺素,和3-甲氧基酪胺.本文是一名53岁的男性糖尿病和高血压患者的病例报告,该患者一直出现盗汗等症状,经常感冒,减肥,食欲降低,和广泛性焦虑。患者出现盆腔疼痛并寻求医疗护理,导致腹部MRI扫描显示右肾上腺肿块。发现患者的血浆间肾上腺素水平比正常范围高四倍。腹部和骨盆的对比CT扫描显示右肾上腺的尺寸增加,边缘清晰。诊断为右肾上腺嗜铬细胞瘤。病人接受了右腹腔镜肾上腺切除术,这导致间肾上腺素水平降低和血压读数正常。患者在术后期间表现出良好的临床进展,为此,它决定出院回家。
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