PDF(Pubmed)
Abstract：
Involvement of the cervix with acute lymphoblastic leukaemia (ALL) is extremely rare. In this case report, we discuss an unmarried woman in her early 20s, who presented in the emergency with lower abdominal pain and irregular vaginal bleeding for 1 month. Clinical examination and imaging revealed a large cervical mass probably neoplastic with obstructive uropathy. On evaluation, she was diagnosed incidentally with CALLA-positive precursor B cell ALL in peripheral blood flow cytometry. Involvement of B cell ALL in cervical mass was confirmed by histopathological examination of cervical biopsy and immunohistochemistry markers. Her history was not suggestive of signs and symptoms pertaining to leukaemia. Literature is sparse with only a few cases reporting cervical leukaemic infiltration. The present case report is a rarest case where the primary/initial presentation of precursor B cell ALL was seen with cervical involvement and obstructive uropathy mimicking characteristics of advanced cervical malignancy.
摘要：
宫颈与急性淋巴细胞白血病（ALL）的关系极为罕见。在这个案例报告中,我们讨论一个20出头的未婚女子,在紧急情况下出现下腹痛和不规则阴道出血1个月。临床检查和影像学检查显示，宫颈大肿块可能是梗阻性尿路病变。关于评估，在外周血流式细胞术中偶然诊断为CALLA阳性前体B细胞ALL.通过宫颈活检和免疫组织化学标记的组织病理学检查证实了B细胞ALL在宫颈肿块中的参与。她的病史没有提示与白血病有关的体征和症状。文献很少，只有少数病例报告宫颈白血病浸润。本病例报告是最罕见的病例，其中发现前B细胞ALL的主要/初始表现为宫颈受累和阻塞性尿路病变，模仿了晚期宫颈恶性肿瘤的特征。
