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Abstract：
OBJECTIVE: To identify predictors for long-term relapse of orthodontic therapy in patients with cleft lip and palate (CLP).
METHODS: Patients with uni- and bilateral non-syndromal CLP were followed up at least two years after completion of their orthodontic therapy. Plaster casts of the start of treatment (T1), after completion of treatment (T2), and at follow-up (T3) were measured using the modified Huddart Bodenham Index. Characteristics of multidisciplinary therapy were taken from the patient files. Potentially influencing factors of relapse were investigated using logistic regression analyses and Spearman correlations.
RESULTS: In total 58.07% of the included 31 patients showed a stable treatment outcome at follow-up after an average of 6.9 years. Even if relapse occurred, 61.54% of these patients still showed improvement regarding their occlusion compared to baseline. Predictors for the occurrence of relapse were the severity of dysgnathia at baseline (p = 0.039) and the extent of therapeutic change (p = 0.041). The extent of therapeutic change was additionally a predictor for the extent of post-therapeutic relapse (ρ = 0.425; p = 0.019).
CONCLUSIONS: Patients with CLP benefit from their orthodontic therapy in the long term despite an increased tendency to relapse.
CONCLUSIONS: Results of this long-term study could be used to adapt the treatment concept for patients with CLP and reinforce the significance of a patient-centered orthodontic treatment concept for affected patients.
METHODS: Patients with uni- and bilateral non-syndromal CLP were followed up at least two years after completion of their orthodontic therapy. Plaster casts of the start of treatment (T1), after completion of treatment (T2), and at follow-up (T3) were measured using the modified Huddart Bodenham Index. Characteristics of multidisciplinary therapy were taken from the patient files. Potentially influencing factors of relapse were investigated using logistic regression analyses and Spearman correlations.
RESULTS: In total 58.07% of the included 31 patients showed a stable treatment outcome at follow-up after an average of 6.9 years. Even if relapse occurred, 61.54% of these patients still showed improvement regarding their occlusion compared to baseline. Predictors for the occurrence of relapse were the severity of dysgnathia at baseline (p = 0.039) and the extent of therapeutic change (p = 0.041). The extent of therapeutic change was additionally a predictor for the extent of post-therapeutic relapse (ρ = 0.425; p = 0.019).
CONCLUSIONS: Patients with CLP benefit from their orthodontic therapy in the long term despite an increased tendency to relapse.
CONCLUSIONS: Results of this long-term study could be used to adapt the treatment concept for patients with CLP and reinforce the significance of a patient-centered orthodontic treatment concept for affected patients.
摘要：
目的：确定唇腭裂（CLP）患者正畸治疗长期复发的预测因素。
方法：在完成正畸治疗后，对患有单发和双侧非综合征CLP的患者进行至少两年的随访。治疗开始时的石膏模型(T1),治疗完成后（T2），并在随访（T3）时使用改良的HuddartBodenham指数进行测量。多学科治疗的特点取自患者档案。使用逻辑回归分析和Spearman相关性研究了复发的潜在影响因素。
结果：纳入的31例患者中，有58.07%在平均6.9年的随访中显示出稳定的治疗结果。即使复发，与基线相比，这些患者中61.54％的患者在闭塞方面仍表现出改善。复发发生的预测因素是基线时颌下障碍的严重程度（p=0.039）和治疗改变的程度（p=0.041）。治疗变化的程度也是治疗后复发程度的预测因子(ρ=0.425;p=0.019)。
结论：CLP患者长期受益于正畸治疗，尽管复发倾向增加。
结论：这项长期研究的结果可用于适应CLP患者的治疗理念，并加强以患者为中心的正畸治疗理念对受影响患者的意义。
方法：在完成正畸治疗后，对患有单发和双侧非综合征CLP的患者进行至少两年的随访。治疗开始时的石膏模型(T1),治疗完成后（T2），并在随访（T3）时使用改良的HuddartBodenham指数进行测量。多学科治疗的特点取自患者档案。使用逻辑回归分析和Spearman相关性研究了复发的潜在影响因素。
结果：纳入的31例患者中，有58.07%在平均6.9年的随访中显示出稳定的治疗结果。即使复发，与基线相比，这些患者中61.54％的患者在闭塞方面仍表现出改善。复发发生的预测因素是基线时颌下障碍的严重程度（p=0.039）和治疗改变的程度（p=0.041）。治疗变化的程度也是治疗后复发程度的预测因子(ρ=0.425;p=0.019)。
结论：CLP患者长期受益于正畸治疗，尽管复发倾向增加。
结论：这项长期研究的结果可用于适应CLP患者的治疗理念，并加强以患者为中心的正畸治疗理念对受影响患者的意义。
