PDF(Pubmed)
Abstract：
Primary intracranial meningeal melanomas are rare. Diagnosing primary meningeal melanomas mostly involves comprehensive assessment through clinical and radiological means. This evaluation should encompass a detailed dermal and ophthalmic examination. Any suspicious lesion must be biopsied and examined microscopically. This is crucial not only to differentiate primary intracranial melanoma from other brain tumors but also to rule out metastases from potential sources of primary cutaneous or non-cutaneous melanomas. Surgery is considered the mainstay of treatment. Despite melanomas being generally considered radio- and chemo-resistant tumors, adjuvant radiotherapy and chemotherapy still play a crucial role in their management. The treatment landscape for primary meningeal melanoma is continually evolving, with ongoing research aiming to improve outcomes for patients with this challenging disease.
摘要：
原发性颅内脑膜黑素瘤罕见。诊断原发性脑膜黑素瘤主要涉及通过临床和放射学手段进行综合评估。该评估应包括详细的皮肤和眼科检查。任何可疑病变必须进行活检和显微镜检查。这不仅对于区分原发性颅内黑色素瘤与其他脑肿瘤至关重要，而且对于排除原发性皮肤或非皮肤黑色素瘤的潜在来源的转移至关重要。手术被认为是治疗的主要手段。尽管黑色素瘤通常被认为是放射性和化学耐药性肿瘤，辅助放疗和化疗在它们的管理中仍然起着至关重要的作用。原发性脑膜黑色素瘤的治疗前景在不断发展，正在进行的研究旨在改善这种具有挑战性的疾病患者的预后。
