Abstract：
In dry skin (DS), skin-barrier function is easily disturbed and moisturizing factors in the stratum corneum are reduced. Despite being a common condition, DS is often overlooked in patients with advanced age or comorbid diseases. In September 2022, specialists in dermatology and skin care met to discuss unmet needs and management of patients with DS with existing medical conditions or DS induced by ongoing pharmacological treatments. There was consensus about the need to improve the current understanding and management of DS in patients with comorbidities, including type 2 diabetes, chronic kidney disease, radiodermatitis, and photodamaged skin. Clinical guidance related to optimal treatment of DS in patients with advanced age or comorbid diseases is needed. Dexpanthenol-containing emollients have been shown to provide rapid relief from the symptoms and clinical signs of skin inflammation and are well-tolerated and effective in terms of moisturizing and soothing DS and maintaining skin-barrier function. Thus, dexpanthenol-containing emollients may play an important role in future management of DS. Further research is needed to elucidate the efficacy of dexpanthenol across the spectrum of DS, irrespective of comorbidity status or age.
摘要：
在干性皮肤（DS），皮肤屏障功能容易受到干扰，角质层中的保湿因子减少。尽管是一种常见的情况，在高龄或合并症患者中，DS常常被忽视。2022年9月，皮肤病学和皮肤护理专家开会讨论了DS患者的需求和管理，这些患者具有现有的医疗条件或正在进行的药物治疗引起的DS。有共识，有必要提高目前对DS的了解和管理的合并症患者，包括2型糖尿病,慢性肾病,放射性皮炎,和光损伤的皮肤。需要与高龄或合并症患者DS的最佳治疗相关的临床指导。已显示含有右泛醇的润肤剂提供对皮肤炎症的症状和临床体征的快速缓解,并且在保湿和舒缓DS以及维持皮肤屏障功能方面具有良好的耐受性和有效性。因此，含有右泛醇的润肤剂可能在DS的未来管理中起重要作用。需要进一步的研究来阐明右泛醇在DS光谱中的功效，无论合并症状态或年龄。
