Abstract：
Parkinson\'s disease (PD) affects Quality of Life (QoL), since it is responsible for cognitive impairment, non-motor, and motor symptoms. Outcome measures are fundamental for evaluating treatment\'s effect on QoL over time. This systematic review aimed to identify the psychometric properties of PDQ-39 and PDQ-8 in the different populations in which they were validated. The electronic databases systematically searched are MEDLINE (via PubMed), CINAHL, SCOPUS, and Web of Science; the research was conducted in July 2023. The psychometric properties considered were those of the COnsensus-based Standards for the selection of health Measurement Instruments (COSMIN) checklist. Risk of bias was assessed using the COSMIN checklist. The search identified 1306 articles. 398 duplicates were eliminated; 908 articles were analyzed reading title and abstract; 799 were finally excluded because used PDQ-39 and PDQ-8 as outcome measures or were not dealing with psychometric properties; 66 articles were excluded after reading the full text. 43 articles were included in the review; meta-analysis showed all the Cronbach\'s alpha values were statistically significant for all the subscales of PDQ-39 and PDQ-8. PDQ-39 demonstrated to be a specific HRQoL questionnaire that is correlated with generic HRQoL questionnaires, in fact in many studies included in the review, correlations with SF-36 were found. In the last studies about psychometric properties of PDQ-8 emerged that it is a practical and informative instrument that can be easily used in clinical settings, especially in busy ones, but also in large-scale studies in which a brief instrument would be preferred.
摘要：
帕金森病（PD）影响生活质量（QoL），因为它是认知障碍的原因，非运动，和运动症状。结果指标是评估治疗对QoL随时间变化的影响的基础。本系统综述旨在确定PDQ-39和PDQ-8在经过验证的不同人群中的心理测量特性。系统搜索的电子数据库是MEDLINE(通过PubMed)，CINAHL,Scopus,和WebofScience；这项研究于2023年7月进行。所考虑的心理测量特性是基于Consensus的健康测量仪器（COSMIN）清单选择标准的特性。使用COSMIN检查表评估偏倚风险。搜索确定了1306个文章。消除了398个重复项；分析了908篇文章的标题和摘要；最终排除了799篇，因为使用PDQ-39和PDQ-8作为结果指标或未处理心理测量特性；阅读全文后排除了66篇文章。43篇文章被纳入评价；荟萃分析显示，所有Cronbachα值对于PDQ-39和PDQ-8的所有分量表都具有统计学意义。PDQ-39被证明是与通用HRQoL问卷相关的特定HRQoL问卷，事实上，在这篇综述中的许多研究中，发现与SF-36相关。在关于PDQ-8的心理测量特性的最后研究中，它是一种实用且信息丰富的工具，可以很容易地用于临床环境。尤其是在忙碌的时候，但在大规模研究中也是如此，在这些研究中，一个简短的工具将是首选。
