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Abstract：
Abdominal pain has been rarely reported in individuals infected with Toxoplasma gondii (T. gondii). The aim of this study was to determine the association between T. gondii infection and abdominal pain. Two hundred and ninety-nine patients with abdominal pain (cases) and 299 age- and gender-matched people without abdominal pain (controls) were tested for anti-T. gondii IgG and IgM antibodies. Twenty-four (8.0%) of the 299 cases and 12 (4.0%) of the 299 controls were positive for anti-T. gondii IgG antibodies (OR: 2.08; 95% CI: 1.02-4.25; P = 0.03). The seroprevalence of T. gondii infection was significantly higher in women with frequent abdominal pain than in women without this clinical feature (OR: 2.30; 95% CI: 1.06-4.96; P = 0.02). Twelve (4.0%) of the 299 cases and 7 (2.3%) of the 299 controls had high (>150 IU mL-1) anti-T. gondii IgG antibody levels (OR: 1.74; 95% CI: 0.67-4.49; P = 0.24). Seven (29.2%) of the 24 cases with anti-T. gondii IgG antibodies and 3 (25.0%) of the 12 controls with anti-T. gondii IgG antibodies were positive to anti-T. gondii IgM antibodies (OR: 1.23; 95% CI: 0.25-5.97; P = 1.00). Results suggest an association between T. gondii infection and frequent abdominal pain. Further research to confirm this association should be conducted.
摘要：
在感染弓形虫的个体中很少报道腹痛（T。gondii）。这项研究的目的是确定弓形虫感染与腹痛之间的关系。对二百九十九名腹痛患者（病例）和299名年龄和性别匹配的无腹痛患者（对照）进行了抗T。弓形虫IgG和IgM抗体。299例病例中有24例（8.0％）和299例对照中有12例（4.0％）抗T。gondiiIgG抗体（OR：2.08；95％CI：1.02-4.25；P=0.03）。经常腹痛的女性弓形虫感染的血清阳性率明显高于没有这种临床特征的女性（OR：2.30；95％CI：1.06-4.96；P=0.02）。299例病例中有12例（4.0％）和299例对照中有7例（2.3％）具有高（>150IUmL-1）抗T。gondiiIgG抗体水平（OR：1.74；95％CI：0.67-4.49；P=0.24）。24例抗T.刚地IgG抗体和3（25.0％）的12个对照与抗T。gondiiIgG抗体对抗T.gondiiIgM抗体(OR:1.23;95%CI:0.25-5.97;P=1.00)。结果表明弓形虫感染与频繁腹痛之间存在关联。应该进行进一步的研究以确认这种关联。
