PDF(Pubmed)
Abstract：
UNASSIGNED: The purpose of this study was to evaluate the effects of posterior vitreous detachment (PVD) on visual quality in patients with high myopia, as well as investigate the associated factors of photopic and mesopic contrast sensitivity function (CSF) in high myopia.
UNASSIGNED: Visual quality was comprehensively assessed in patients with high myopia. Visual acuity, contrast sensitivity (CS) at four spatial frequencies (3, 6, 12, and 18 cycles per degree [c.p.d.]) under photopic and mesopic conditions, as well as the modulation transfer function cutoff value (MTFcutoff), the objective scatter index (OSI), the Strehl ratio (SR), and internal aberrations, were measured in this cross-sectional study.
UNASSIGNED: This study included 94 eyes from 47 subjects with bilateral high myopia, including 23 eyes with complete PVD (cPVD), 21 eyes with partial PVD (pPVD), and 50 eyes without PVD (nPVD). There was no significant difference in visual quality between the cPVD group and the nPVD group. Whereas in eyes with pPVD, there was a degradation of overall photopic CSF (versus nPVD, P = 0.048), photopic CS at 3 c.p.d. (versus cPVD, P = 0.009 and versus nPVD, P = 0.032), photopic CS at 18 c.p.d. (versus nPVD, P = 0.033), overall mesopic CSF (versus nPVD, P = 0.033), and secondary astigmatism (versus cPVD, P = 0.044). Under photopic conditions, the factors affecting CSF were pPVD and SR, whereas the factors affecting mesopic CSF were pPVD, OSI, and ganglion cell-inner plexiform layer thickness.
UNASSIGNED: The pPVD impaired visual quality in patients with high myopia compared to nPVD or cPVD, and pPVD could be a factor explaining CSF at both photopic and mesopic illumination.
UNASSIGNED: Clinicians need to closely monitor patients with high myopia with pPVD due to the potential decline in visual quality and the development of vitreoretinal disorders.
UNASSIGNED: Visual quality was comprehensively assessed in patients with high myopia. Visual acuity, contrast sensitivity (CS) at four spatial frequencies (3, 6, 12, and 18 cycles per degree [c.p.d.]) under photopic and mesopic conditions, as well as the modulation transfer function cutoff value (MTFcutoff), the objective scatter index (OSI), the Strehl ratio (SR), and internal aberrations, were measured in this cross-sectional study.
UNASSIGNED: This study included 94 eyes from 47 subjects with bilateral high myopia, including 23 eyes with complete PVD (cPVD), 21 eyes with partial PVD (pPVD), and 50 eyes without PVD (nPVD). There was no significant difference in visual quality between the cPVD group and the nPVD group. Whereas in eyes with pPVD, there was a degradation of overall photopic CSF (versus nPVD, P = 0.048), photopic CS at 3 c.p.d. (versus cPVD, P = 0.009 and versus nPVD, P = 0.032), photopic CS at 18 c.p.d. (versus nPVD, P = 0.033), overall mesopic CSF (versus nPVD, P = 0.033), and secondary astigmatism (versus cPVD, P = 0.044). Under photopic conditions, the factors affecting CSF were pPVD and SR, whereas the factors affecting mesopic CSF were pPVD, OSI, and ganglion cell-inner plexiform layer thickness.
UNASSIGNED: The pPVD impaired visual quality in patients with high myopia compared to nPVD or cPVD, and pPVD could be a factor explaining CSF at both photopic and mesopic illumination.
UNASSIGNED: Clinicians need to closely monitor patients with high myopia with pPVD due to the potential decline in visual quality and the development of vitreoretinal disorders.
摘要：
■这项研究的目的是评估高度近视患者的玻璃体后脱离（PVD）对视觉质量的影响，以及探讨高度近视患者明视和中视对比敏感功能（CSF）的相关因素。
■对高度近视患者的视觉质量进行综合评估。视敏度,对比敏感度（CS）在四个空间频率（3，6，12和18周期每度[c.p.d.]）在明视和中视条件下，以及调制传递函数截止值(MTFcutoff)，客观散射指数(OSI)，斯特雷尔比率(SR)，和内部像差，在这项横断面研究中进行了测量。
■这项研究包括47名双侧高度近视受试者的94只眼，包括23眼完全PVD（cPVD），21眼部分PVD（pPVD），50只眼无PVD(nPVD)。cPVD组与nPVD组视觉质量无显著差别。而在pPVD的眼中，总体明视CSF降解(与nPVD相比，P=0.048),在3c.p.d.(与cPVD，P=0.009和nPVD，P=0.032),在18c.p.d.(与nPVD，P=0.033),总体介孔CSF（与nPVD，P=0.033),和继发性散光(与cPVD，P=0.044)。在明视条件下，影响CSF的因素是pPVD和SR，而影响介孔CSF的因素是pPVD，OSI,神经节细胞内丛状层厚度。
■与nPVD或cPVD相比，高度近视患者的pPVD视觉质量受损，pPVD可能是在明视和中视照明下解释CSF的一个因素。
■由于视觉质量的潜在下降和玻璃体视网膜疾病的发展，临床医生需要密切监测患有pPVD的高度近视患者。
■对高度近视患者的视觉质量进行综合评估。视敏度,对比敏感度（CS）在四个空间频率（3，6，12和18周期每度[c.p.d.]）在明视和中视条件下，以及调制传递函数截止值(MTFcutoff)，客观散射指数(OSI)，斯特雷尔比率(SR)，和内部像差，在这项横断面研究中进行了测量。
■这项研究包括47名双侧高度近视受试者的94只眼，包括23眼完全PVD（cPVD），21眼部分PVD（pPVD），50只眼无PVD(nPVD)。cPVD组与nPVD组视觉质量无显著差别。而在pPVD的眼中，总体明视CSF降解(与nPVD相比，P=0.048),在3c.p.d.(与cPVD，P=0.009和nPVD，P=0.032),在18c.p.d.(与nPVD，P=0.033),总体介孔CSF（与nPVD，P=0.033),和继发性散光(与cPVD，P=0.044)。在明视条件下，影响CSF的因素是pPVD和SR，而影响介孔CSF的因素是pPVD，OSI,神经节细胞内丛状层厚度。
■与nPVD或cPVD相比，高度近视患者的pPVD视觉质量受损，pPVD可能是在明视和中视照明下解释CSF的一个因素。
■由于视觉质量的潜在下降和玻璃体视网膜疾病的发展，临床医生需要密切监测患有pPVD的高度近视患者。
