Abstract：
Objective:This study analyzed the pure tone audiometry results of the affected ear and the contralateral ear of unilateral Meniere\'s disease to investigate the correlation of the hearing threshold of the contralateral ear and the hearing prognosis of unilateral Meniere\'s disease. Methods:In this study, the follow-up data of 135 patients with unilateral Meniere\'s disease in Beijing Tongren Hospital were used to analyze the pure tone audiometry results of the affected and contralateral ears at the first visit and 1 year later. Results:①At the first visit, there was no statistically significant difference between the mean hearing thresholds of the affected ear in the normal hearing group and the high-frequency hearing loss group of the contralateral ear（P>0.05）. ②The range of improvement of hearing thresholds in the affected ear was greater in the contralateral ear normal hearing group than in the contralateral ear high-frequency hearing loss group. In the normal hearing group of the contralateral ear, the hearing thresholds of the affected ear at 0.25 kHz（P<0.01）, 0.50 kHz（P<0.01）, 1.00 kHz（P<0.01）, and 2.00 kHz（P<0.05） were significantly improved; and in the high-frequency hearing loss group of the contralateral ear, the hearing thresholds at 0.25 kHz（P<0.01） hearing thresholds improved significantly, and there was no significant difference between the rest of the frequencies before and after treatment（P>0.05）. A consistent pattern was observed in both higher and lower age groups. ③After 1 year of follow-up, the low and mid-frequency hearing of the affected ear improved. 0.25 kHz（P<0.01）, 0.50 kHz（P<0.01）, 1.00 kHz（P<0.01） hearing thresholds improved significantly; 8.00 kHz hearing thresholds decreased slightly（P<0.05）. Conclusion:After standardized treatment, the results of 1-year follow-up suggested that the low-frequency hearing of MD patients could be improved, but the high-frequency hearing was slightly decreased. The hearing prognosis of the affected ear with normal hearing threshold of the contralateral ear may be better.
目的：通过分析单侧梅尼埃病患耳和对侧耳的纯音测听结果，探讨对侧耳的听阈与单侧梅尼埃病患耳听阈转归的关系。 方法：纳入在北京同仁医院确诊并连续入组的单侧梅尼埃病135例患者，在规范治疗下完成1年的随访，分析患耳和对侧耳在首次就诊时和1年后的纯音听阈结果。 结果：①入组时，对侧耳听力正常组和高频听力下降组的患耳平均听阈差异无统计学意义（P>0.05）。②对侧耳听力正常组的患耳听阈改善范围较对侧耳高频听力下降组更大。在对侧耳听力正常组中，患耳0.25 kHz（P<0.01）、0.50 kHz（P<0.01）、1.00 kHz（P<0.01）、2.00 kHz（P<0.05）听阈显著改善；在对侧耳高频听力下降组中，仅有0.25 kHz（P<0.01）听阈获得改善，其他常规测听频率在治疗前后差异均无统计学意义（P>0.05）。此现象在高年龄组和低年龄组中结果一致。③全部患者经过规范治疗并完成1年随访后，患耳的低中频听阈获得改善。0.25 kHz（P<0.01）、0.50 kHz（P<0.01）、1.00 kHz（P<0.01）听阈显著改善；8.00 kHz听阈略有下降（P<0.05）。 结论：梅尼埃病患者经过规范治疗后，低中频听力可获良好的改善效果，但高频听力略有下降，且对侧耳听阈正常的患耳较高频听阈异常者的听阈改善更为明显。.
目的：通过分析单侧梅尼埃病患耳和对侧耳的纯音测听结果，探讨对侧耳的听阈与单侧梅尼埃病患耳听阈转归的关系。 方法：纳入在北京同仁医院确诊并连续入组的单侧梅尼埃病135例患者，在规范治疗下完成1年的随访，分析患耳和对侧耳在首次就诊时和1年后的纯音听阈结果。 结果：①入组时，对侧耳听力正常组和高频听力下降组的患耳平均听阈差异无统计学意义（P>0.05）。②对侧耳听力正常组的患耳听阈改善范围较对侧耳高频听力下降组更大。在对侧耳听力正常组中，患耳0.25 kHz（P<0.01）、0.50 kHz（P<0.01）、1.00 kHz（P<0.01）、2.00 kHz（P<0.05）听阈显著改善；在对侧耳高频听力下降组中，仅有0.25 kHz（P<0.01）听阈获得改善，其他常规测听频率在治疗前后差异均无统计学意义（P>0.05）。此现象在高年龄组和低年龄组中结果一致。③全部患者经过规范治疗并完成1年随访后，患耳的低中频听阈获得改善。0.25 kHz（P<0.01）、0.50 kHz（P<0.01）、1.00 kHz（P<0.01）听阈显著改善；8.00 kHz听阈略有下降（P<0.05）。 结论：梅尼埃病患者经过规范治疗后，低中频听力可获良好的改善效果，但高频听力略有下降，且对侧耳听阈正常的患耳较高频听阈异常者的听阈改善更为明显。.
摘要：
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