关键词: NHANSE cross-sectional study emotional disorders post-stroke depression (PSD) systemic immune-inflammation index (SII)

来  源:   DOI:10.3389/fneur.2024.1330338   PDF(Pubmed)

Abstract:
UNASSIGNED: Less research has linked the Systemic Immune Inflammatory Index (SII) with post-stroke depression (PSD). This study aims to look at any potential connections between SII and PSD.
UNASSIGNED: The National Health and Nutrition Examination Survey (NHANES), conducted in a population that embodied complete SII and stroke data from 2005 to 2020, was used to perform the current cross-sectional survey. A fitted smoothed curve was used to depict the nonlinear link between SII and PSD, and multiple linear regression analysis demonstrated a positive correlation between SII and PSD.
UNASSIGNED: Multiple linear regression analysis showed that SII and PSD were markedly related [1.11(1.05, 1.17)]. Interaction tests showed that the association between SII and PSD was not statistically different between strata, and age, sex, BMI, income poverty ratio, education level, smoking status, diabetes mellitus, coronary heart disease, and heart failure did not have a significant effect on this positive association (p > 0.05 for interaction). In addition, a nonlinear association between SII and PSD was found using a two-stage linear regression model.
UNASSIGNED: The results of our research support the existence of a significant positive correlation between SII levels and PSD. Further prospective trials are required to comprehend SII, which is for the PSD thoroughly.
摘要:
较少研究将全身免疫炎症指数(SII)与卒中后抑郁(PSD)联系起来。本研究旨在研究SII和PSD之间的任何潜在联系。
国家健康和营养调查(NHANES),在包含2005年至2020年完整SII和卒中数据的人群中进行的研究被用于进行当前的横断面调查.拟合平滑曲线用于描述SII和PSD之间的非线性联系,多元线性回归分析显示SII与PSD呈正相关。
多元线性回归分析显示SII与PSD呈显著相关[1.11(1.05,1.17)]。交互检验表明,SII和PSD之间的关联在地层之间没有统计学差异,和年龄,性别,BMI,收入贫困率,教育水平,吸烟状况,糖尿病,冠心病,心力衰竭对这种正相关没有显著影响(交互作用p>0.05)。此外,使用两阶段线性回归模型发现SII与PSD之间存在非线性关联.
我们的研究结果支持SII水平与PSD之间存在显着正相关。需要进一步的前瞻性试验来理解SII,这是彻底的PSD。
公众号