PDF(Pubmed)
Abstract：
Meningitis caused by Salmonella enterica can be a fatal condition that is more common in low- and middle-income countries and uncommon in infants. This case of a 2-month-old male infant reported Salmonella meningitis symptoms, such as fever, irritability, altered sensorium, and diarrhoea. Clinical examination revealed bulging anterior fontanelles, dehydration, and sunken eyes. Screening for normal hearing, cranial ultrasound, and magnetic resonance imaging (MRI) revealed no brain abnormalities. A cerebrospinal fluid (CSF) culture revealed gram-negative Salmonella enterica bacilli. Treatment with meropenem and ampicillin was initiated after antibiotic susceptibility testing showed sensitivity. The patient\'s cerebrospinal fluid parameters and bacterial growth improved after antibiotic therapy. Two weeks later, the baby was neurologically healthy and discharged. Paediatricians should be aware that Salmonella enterica can cause meningitis in children with non-specific symptoms.
摘要：
由肠沙门氏菌引起的脑膜炎可能是一种致命的疾病，在低收入和中等收入国家更常见，在婴儿中并不常见。这例2个月大男婴报告沙门菌脑膜炎症状,比如发烧，烦躁，改变的感官，和腹泻。临床检查显示前fontanelles膨出，脱水,和凹陷的眼睛。听力正常筛查,头颅超声,磁共振成像（MRI）显示没有脑部异常。脑脊液（CSF）培养显示革兰氏阴性沙门氏菌。抗生素药敏试验显示敏感性后，开始使用美罗培南和氨苄西林治疗。抗生素治疗后，患者的脑脊液参数和细菌生长得到改善。两周后,婴儿神经健康，出院。儿科医生应该意识到，肠道沙门氏菌可导致具有非特异性症状的儿童脑膜炎。
