PDF(Pubmed)
Abstract：
We present a rare case of a 25-year-old woman who developed idiopathic portal hypertension and ascites four days after delivering a stillborn child at term. She had no previous liver illness or risk factors for portal vein thrombosis. Investigations revealed a dilated portal vein, esophageal varices, and high serum-albumin gradient ascites, all of which point to a presinusoidal etiology of portal hypertension. There was no indication of cirrhosis, hepatic or portal vein thrombosis, metabolic or autoimmune liver diseases, or persistent infections. She was treated with antibiotics, diuretics, and beta-blockers, and she underwent a therapeutic paracentesis. The etiology of her portal hypertension remains undetermined. Idiopathic portal hypertension is a rare condition of unknown etiology, characterized by portal hypertension without cirrhosis or thrombosis. It is linked to several risk factors and histological abnormalities, and it can be accompanied by portal hypertension consequences, such as variceal hemorrhage and ascites. The diagnosis is made using clinical criteria and the elimination of alternative causes of portal hypertension. Management is mostly symptomatic, intending to avoid and treat portal hypertension consequences. The prognosis varies according to the underlying etiology and presence of complications.
摘要：
我们介绍了一例25岁女性的罕见病例，该女性在足月分娩死胎四天后出现特发性门静脉高压和腹水。她以前没有肝病或门静脉血栓形成的危险因素。调查显示门静脉扩张,食管静脉曲张,和高血清白蛋白梯度腹水，所有这些都指向门脉高压的窦前病因。没有肝硬化的迹象,肝或门静脉血栓形成，代谢性或自身免疫性肝病，或持续性感染。她接受了抗生素治疗，利尿剂,和β受体阻滞剂，她接受了治疗性穿刺.她的门静脉高压症的病因仍未确定。特发性门静脉高压是一种病因不明的罕见疾病，特征为无肝硬化或血栓形成的门静脉高压症。它与几个危险因素和组织学异常有关，它可能伴随着门静脉高压的后果，如静脉曲张出血和腹水。诊断是根据临床标准和消除门脉高压的其他原因进行的。管理主要是有症状的，打算避免和治疗门静脉高压的后果。预后根据潜在的病因和并发症的存在而变化。
