Abstract:
This case report highlights the clinical challenge and need to distinguish Sweet syndrome and erythema nodosum (EN) in a 50-year-old woman with newly initiated azathioprine for inflammatory bowel disease. While she initially presented with clinical features concerning for drug-induced Sweet syndrome, a subsequent histopathological examination confirmed early-stage EN. Both Sweet syndrome and EN share common triggers and therapeutic responses, but have distinctive clinical characteristics. Subtle histologic differences also exist in lesion distribution and depth of infiltration. This case underscores the need for accurate differentiation in patients with inflammatory bowel disease to initiate appropriate management and avoid potential complications.
摘要:
该病例报告强调了临床挑战,需要区分Sweet综合征和结节性红斑(EN)在一名50岁女性中,新开始使用硫唑嘌呤治疗炎症性肠病。虽然她最初提出了有关药物诱发的Sweet综合征的临床特征,随后的组织病理学检查证实早期EN.Sweet综合征和EN都有共同的触发因素和治疗反应,但具有鲜明的临床特征。病变分布和浸润深度也存在细微的组织学差异。此病例强调需要对炎症性肠病患者进行准确的区分,以开始适当的治疗并避免潜在的并发症。