关键词: Poisoning case report herbicide herbicide toxicity mortality multi-organ failure paraquat toxicology

来  源:   DOI:10.1177/2050313X241240098   PDF(Pubmed)

Abstract:
Paraquat, a highly toxic herbicide, accounts for a substantial number of poisoning-related fatalities, primarily prevalent in agricultural regions. The ingestion gives rise to severe complications affecting various organs, including the lungs, gastrointestinal tract, kidneys and liver. This report details the case of an 18-year-old male who had been using cannabis for a year and inadvertently ingested paraquat. He presented at the emergency room exhibiting symptoms of vomiting characterized by hematemesis and regurgitated food particles, along with heartburn, dysphagia and reduced urine output. Given the absence of a specific antidote, the prognosis for paraquat poisoning remains generally unfavourable. Diagnosis relies on circumstantial evidence and clinical manifestations, necessitating a focus on supportive care. Presently, no specific antidote for paraquat poisoning is available. Efforts should concentrate on preventive measures, efficient decontamination strategies and vigilant stabilization protocols in instances of exposure.
摘要:
百草枯,一种剧毒的除草剂,造成大量与中毒有关的死亡,主要在农业地区流行。摄入会导致影响各种器官的严重并发症,包括肺,胃肠道,肾脏和肝脏。本报告详细介绍了一名18岁男性的情况,该男性使用大麻一年,无意中摄入了百草枯。他出现在急诊室,表现出呕吐症状,特征是呕血和返流食物颗粒,伴随着胃灼热,吞咽困难和尿量减少。鉴于缺乏特定的解毒剂,百草枯中毒的预后总体上仍然不利。诊断依赖于间接证据和临床表现,需要专注于支持性护理。目前,没有针对百草枯中毒的特定解毒剂。努力应集中在预防措施上,在暴露的情况下,有效的去污策略和警惕的稳定方案。
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