PDF(Pubmed)
Abstract：
A gastric ulcer is a tear in the stomach lining that manifests as abdominal pain, nausea, vomiting, and weight loss. Its occurrence is lesser in children as compared to adults and its incidence in children ranges between 2% and 8%. Helicobacter pylori and nonsteroidal anti-inflammatory drugs are the most common causes of gastric ulcers. In our case, we report a 2.5-month-old male who presented with severe pallor, hematemesis, and melena with normal weight gain. The patient\'s mother was infected with COVID-19 a month ago and recovered within 5 days but kept using aspirin and nonsteroidal anti-inflammatory drugs for a month during breastfeeding. An upper gastrointestinal endoscopy revealed a gastric ulcer and the Helicobacter pylori antigen was positive in the biopsy. A COVID-19 infection was detected later in the patient. The patient was administered proton pump inhibitor, clarithromycin, and amoxicillin for Helicobacter pylori antigen and symptomatic treatment for COVID-19. This case report shows that a stomach ulcer can appear in infancy, but opportune interventions such as timely diagnosis and treatment can solve the problem. It also marks the pathophysiological connection between Helicobacter pylori and gastric ulcer.
摘要：
胃溃疡是胃壁的撕裂，表现为腹痛，恶心,呕吐,和减肥。与成人相比，其在儿童中的发生率较低，在儿童中的发生率在2％至8％之间。幽门螺杆菌和非甾体抗炎药是胃溃疡的最常见原因。在我们的案例中,我们报告了一名2.5个月大的男性，他表现出严重的苍白，呕血,和正常体重增加的黑便.患者的母亲一个月前感染了COVID-19，5天内康复，但在母乳喂养期间使用阿司匹林和非甾体抗炎药一个月。上消化道内窥镜检查显示胃溃疡，活检中幽门螺杆菌抗原阳性。后来在患者中检测到COVID-19感染。病人服用质子泵抑制剂,克拉霉素,阿莫西林用于幽门螺杆菌抗原和COVID-19的对症治疗。这个病例报告显示胃溃疡可以在婴儿期出现，但是及时的诊断和治疗等及时的干预措施可以解决问题。它也标志着幽门螺杆菌和胃溃疡之间的病理生理联系。
