关键词: Lyme disease borreliosis children course cutaneous findings treatment

Mesh : Humans Child Pseudolymphoma Lyme Disease / complications diagnosis epidemiology Erythema Chronicum Migrans / diagnosis drug therapy Skin Diseases Dermatitis

来  源:   DOI:10.1684/ejd.2024.4611

Abstract:
Borreliosis, also known as Lyme disease, is a vector-borne disease caused by different species of the Borrelia burgdorferi complex. It is frequent in Europe and Northern America. The major vectors are ixodoid ticks. Paediatric borreliosis is common and peaks in children between five to nine years. In Europe, the leading symptom of early infection is erythema migrans, in contrast to Northern America where arthritis is the dominating clinical finding. In this review, we focus on Europe, where cutaneous borreliosis is mainly caused by infection with B. afzelii. The cutaneous symptoms include erythema migrans, lymphocytoma, chronic atrophic dermatitis and juxta-articular nodules. In children, lymphocytoma is very common but chronic atrophic dermatitis is rare. Clinical symptoms, diagnosis, peculiarities of childhood disease and treatment are also reviewed. It is important to note that after haematogeneic spread, signs of infection may be non-specific, and this is a challenge for diagnosis.
摘要:
疏螺旋体病,也被称为莱姆病,是由伯氏疏螺旋体复合体的不同物种引起的媒介传播疾病。它在欧洲和北美很常见。主要载体是ixodoid蜱。小儿疏螺旋体病很常见,在5至9岁的儿童中达到高峰。在欧洲,早期感染的主要症状是偏头痛性红斑,与北美相反,在北美,关节炎是主要的临床发现。在这次审查中,我们专注于欧洲,其中皮肤borreliosis主要是由B.afzelii感染引起的。皮肤症状包括偏头痛红斑,淋巴细胞瘤,慢性萎缩性皮炎和近关节结节。在儿童中,淋巴细胞瘤非常常见,但慢性萎缩性皮炎很少见。临床症状,诊断,还回顾了儿童疾病和治疗的特点。重要的是要注意,在造血传播后,感染的迹象可能是非特异性的,这对诊断来说是一个挑战。
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