Mesh : Humans Radiotherapy, Intensity-Modulated Radiotherapy Dosage Radiotherapy Planning, Computer-Assisted Esophageal Neoplasms / radiotherapy Thorax Algorithms Organs at Risk

来  源:   DOI:10.4103/jcrt.jcrt_2171_22

Abstract:
OBJECTIVE: In this study, efficacy of collapsed cone algorithm-generated intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT) were evaluated for treatment of thoracic esophageal cancer.
METHODS: Ten previously treated patients with VMAT were considered for evaluation. The planning parameters were evaluated in terms of max dose, mean dose, Homogeneity Index, Conformity Index for planning target volume, and organ at risk doses. Total monitor unit, treatment time, and gamma passing index were also reported.
RESULTS: The target dose coverage of the VMAT and IMRT plans achieved the clinical dosimetric criteria for all ten patients in the evaluation. Under the condition of equivalent target dose distribution, the VMAT plan\'s Conformity Index, monitor unit, treatment time, and gamma passing index rate were superior than in the IMRT plan, and the result was statistically significant.
CONCLUSIONS: Collapsed cone algorithm-based VMAT can have a more effective and better approach for esophageal cancer than IMRT.
摘要:
目的:在本研究中,对塌陷锥算法产生的调强放疗(IMRT)和体积调强电弧治疗(VMAT)治疗胸段食管癌的疗效进行了评价.
方法:考虑对10名以前接受过VMAT治疗的患者进行评估。根据最大剂量评估计划参数,平均剂量,均匀性指数,规划目标体积的符合性指数,和器官风险剂量。总监控单元,治疗时间,还报告了伽马通过指数。
结果:VMAT和IMRT计划的目标剂量覆盖率达到了评估中所有10名患者的临床剂量标准。在等效靶剂量分布条件下,VMAT计划的合格指数,监控单元,治疗时间,伽马通过指数率优于IMRT计划,结果具有统计学意义。
结论:基于折叠锥算法的VMAT治疗食管癌的方法比IMRT更有效、更好。
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