PDF(Pubmed)
Abstract：
Gastroschisis is the most common congenital defect of the abdominal wall, typically located to the right of the umbilical cord, through which the intestinal loops and viscera exit without being covered by the amniotic membrane. Despite the known risk factors for gastroschisis, there is no consensus on the cause of this malformation. Prenatal ultrasound is useful for diagnosis, prognostic prediction (ultrasonographic markers) and appropriate monitoring of fetal vitality. Survival rate of children with gastroschisis is more than 95% in developed countries; however, complex gastroschisis requires multiple neonatal interventions and is associated with adverse perinatal outcomes. In this article, we conducted a narrative review including embryology, pathogenesis, risk factors, and ultrasonographic markers for adverse neonatal outcomes in fetuses with gastroschisis. Prenatal risk stratification of gastroschisis helps to better counsel parents, predict complications, and prepare the multidisciplinary team to intervene appropriately and improve postnatal outcomes.
摘要：
腹裂是最常见的先天性腹壁缺损,通常位于脐带的右侧，肠环和内脏通过它退出而不被羊膜覆盖。尽管已知胃裂的危险因素，对这种畸形的原因没有共识。产前超声检查有助于诊断，预后预测（超声标记）和适当的胎儿活力监测。在发达国家，腹裂儿童的存活率超过95%；然而，复杂的腹裂需要多种新生儿干预措施,并且与不良围产期结局相关.在这篇文章中,我们进行了叙事回顾，包括胚胎学，发病机制，危险因素，和胎儿腹裂不良新生儿结局的超声标记物。腹裂的产前风险分层有助于更好地建议父母，预测并发症，并准备多学科团队进行适当干预并改善产后结局。
