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Abstract：
OBJECTIVE: In view of the widening gap in survival data between high-income and low-income countries, this study aimed to evaluate the most up-to-date burden of female breast cancer and analyse the leading risk factors in countries and regions in sub-Saharan Africa.
METHODS: An analysis of Global Burden of Disease (GBD) data.
METHODS: The data of incidences, deaths, disability-adjusted life years (DALYs) and age-standardised rates (ASR) were retrieved from GBD Results Tool (1 January 1990─31 December 2019) covering 4 sub-Saharan African regions and 44 countries. The burden estimable to the risk factors of breast cancer was also estimated. All estimates were presented as counts and ASR per 100 000 population.
METHODS: Participants included patients with female breast cancer.
METHODS: Absolute numbers and ASR/estimates of incidence, deaths and DALY of female breast cancer by location in 1990 and 2019, with their percentage changes from 1990 to 2019. The leading risk factors (eg, alcohol consumption) of breast cancer in sub-Saharan Africa.
RESULTS: In sub-Saharan Africa, the incidences of breast cancer increased by 247% in 2019 from 1990, with the highest incidence recorded in Nigeria. The deaths and DALYs of breast cancer increased by 184% and 178%, respectively. From 1990 to 2019, the mortality ASR and DALY ASR increased throughout the region, mostly in Equatorial and Gabon. With varying trends between countries, alcohol consumption and high fasting plasma glucose were noted to be significant contributors to breast cancer deaths between 1990 and 2019.
CONCLUSIONS: The results show the increasing burden of breast cancer in sub-Saharan Africa and provide valuable information on the trends of breast cancer and the risk factors attributable to breast cancer across sociodemographic index, region and country. These findings may inform health policies and improve the rational allocation of health resources.
METHODS: An analysis of Global Burden of Disease (GBD) data.
METHODS: The data of incidences, deaths, disability-adjusted life years (DALYs) and age-standardised rates (ASR) were retrieved from GBD Results Tool (1 January 1990─31 December 2019) covering 4 sub-Saharan African regions and 44 countries. The burden estimable to the risk factors of breast cancer was also estimated. All estimates were presented as counts and ASR per 100 000 population.
METHODS: Participants included patients with female breast cancer.
METHODS: Absolute numbers and ASR/estimates of incidence, deaths and DALY of female breast cancer by location in 1990 and 2019, with their percentage changes from 1990 to 2019. The leading risk factors (eg, alcohol consumption) of breast cancer in sub-Saharan Africa.
RESULTS: In sub-Saharan Africa, the incidences of breast cancer increased by 247% in 2019 from 1990, with the highest incidence recorded in Nigeria. The deaths and DALYs of breast cancer increased by 184% and 178%, respectively. From 1990 to 2019, the mortality ASR and DALY ASR increased throughout the region, mostly in Equatorial and Gabon. With varying trends between countries, alcohol consumption and high fasting plasma glucose were noted to be significant contributors to breast cancer deaths between 1990 and 2019.
CONCLUSIONS: The results show the increasing burden of breast cancer in sub-Saharan Africa and provide valuable information on the trends of breast cancer and the risk factors attributable to breast cancer across sociodemographic index, region and country. These findings may inform health policies and improve the rational allocation of health resources.
摘要：
目标：鉴于高收入国家和低收入国家之间生存数据的差距不断扩大，本研究旨在评估撒哈拉以南非洲国家和地区女性乳腺癌的最新负担,并分析主要危险因素.
方法：对全球疾病负担（GBD）数据的分析。
方法：发病率数据，死亡,残疾调整寿命年(DALYs)和年龄标准化率(ASR)从GBD结果工具(1990年1月1日-2019年12月31日)检索，涵盖4个撒哈拉以南非洲地区和44个国家。还估计了乳腺癌危险因素的负担。所有估计值均以每10万人口的计数和ASR表示。
方法：参与者包括女性乳腺癌患者。
方法：绝对数和ASR/发病率估计值，1990年和2019年女性乳腺癌的死亡和DALY，从1990年到2019年，其百分比变化。主要风险因素(例如，饮酒）撒哈拉以南非洲的乳腺癌。
结果：在撒哈拉以南非洲，与1990年相比,2019年乳腺癌的发病率增加了247%,其中尼日利亚的发病率最高.乳腺癌的死亡人数和DALYs分别增加了184%和178%，分别。从1990年到2019年，整个地区的死亡率ASR和DALYASR都有所增加，主要在赤道和加蓬。随着国家之间趋势的不同，饮酒和高空腹血糖被认为是1990年至2019年间乳腺癌死亡的重要原因.
结论：结果显示撒哈拉以南非洲的乳腺癌负担不断增加，并提供了有关乳腺癌趋势和社会人口统计学指数中乳腺癌风险因素的有价值的信息。地区和国家。这些发现可以为卫生政策提供信息，并改善卫生资源的合理配置。
方法：对全球疾病负担（GBD）数据的分析。
方法：发病率数据，死亡,残疾调整寿命年(DALYs)和年龄标准化率(ASR)从GBD结果工具(1990年1月1日-2019年12月31日)检索，涵盖4个撒哈拉以南非洲地区和44个国家。还估计了乳腺癌危险因素的负担。所有估计值均以每10万人口的计数和ASR表示。
方法：参与者包括女性乳腺癌患者。
方法：绝对数和ASR/发病率估计值，1990年和2019年女性乳腺癌的死亡和DALY，从1990年到2019年，其百分比变化。主要风险因素(例如，饮酒）撒哈拉以南非洲的乳腺癌。
结果：在撒哈拉以南非洲，与1990年相比,2019年乳腺癌的发病率增加了247%,其中尼日利亚的发病率最高.乳腺癌的死亡人数和DALYs分别增加了184%和178%，分别。从1990年到2019年，整个地区的死亡率ASR和DALYASR都有所增加，主要在赤道和加蓬。随着国家之间趋势的不同，饮酒和高空腹血糖被认为是1990年至2019年间乳腺癌死亡的重要原因.
结论：结果显示撒哈拉以南非洲的乳腺癌负担不断增加，并提供了有关乳腺癌趋势和社会人口统计学指数中乳腺癌风险因素的有价值的信息。地区和国家。这些发现可以为卫生政策提供信息，并改善卫生资源的合理配置。
