PDF(Pubmed)
Abstract：
BACKGROUND: Clear cell carcinoma (CCC) is a highly invasive malignant tumor. CCCs of the female reproductive system occur mostly in the endometrium and ovaries and rarely in the cervix. So, it is difficult to diagnose cervical clear cell carcinoma (CCAC) on imaging. This report helps to further deepen our understanding of CCAC.
METHODS: A 39-year-old female patient presented with vaginal discharge with no obvious cause, elevated levels of carcinoembryonic antigen (CEA), CA125, CA153, and squamous cell carcinoma antigen (SCC), and underwent ultrasonography (US) CT and MRI examination in our hospital, which showed a mass in the cervix of the uterus, considered of cervical squamous carcinoma.
METHODS: The cervix biopsy guided by vaginoscope biopsy and immunohistochemistry confirmed CCAC, combined Magnetic Resonance Imaging examination, CCAC with pelvic lymph node metastasis was considered.
RESULTS: The patient refused further treatment and was discharged from hospital.
CONCLUSIONS: CCAC exhibited no specific symptoms, and is slightly different from cervical squamous carcinoma in image features, mainly relying on immunohistochemistry for diagnosis. The reported case raised awareness of CCAC.
METHODS: A 39-year-old female patient presented with vaginal discharge with no obvious cause, elevated levels of carcinoembryonic antigen (CEA), CA125, CA153, and squamous cell carcinoma antigen (SCC), and underwent ultrasonography (US) CT and MRI examination in our hospital, which showed a mass in the cervix of the uterus, considered of cervical squamous carcinoma.
METHODS: The cervix biopsy guided by vaginoscope biopsy and immunohistochemistry confirmed CCAC, combined Magnetic Resonance Imaging examination, CCAC with pelvic lymph node metastasis was considered.
RESULTS: The patient refused further treatment and was discharged from hospital.
CONCLUSIONS: CCAC exhibited no specific symptoms, and is slightly different from cervical squamous carcinoma in image features, mainly relying on immunohistochemistry for diagnosis. The reported case raised awareness of CCAC.
摘要：
背景：透明细胞癌（CCC）是一种高度侵袭性的恶性肿瘤。女性生殖系统的CCC主要发生在子宫内膜和卵巢，很少发生在子宫颈。所以,在影像学上诊断宫颈透明细胞癌（CCAC）很困难。这份报告有助于进一步加深我们对CCAC的理解。
方法：一名39岁女性患者出现阴道分泌物，无明显病因，癌胚抗原（CEA）水平升高，CA125，CA153和鳞状细胞癌抗原（SCC），并在我院接受了超声（US）CT和MRI检查，显示子宫颈有肿块，考虑宫颈鳞癌。
方法：阴道镜引导下宫颈活检及免疫组化证实CCAC，联合磁共振成像检查，考虑CCAC伴盆腔淋巴结转移。
结果：患者拒绝进一步治疗，出院。
结论：CCAC没有表现出特定的症状，在图像特征上与宫颈鳞癌略有不同，主要依靠免疫组织化学进行诊断。报告的病例提高了CCAC的认识。
方法：一名39岁女性患者出现阴道分泌物，无明显病因，癌胚抗原（CEA）水平升高，CA125，CA153和鳞状细胞癌抗原（SCC），并在我院接受了超声（US）CT和MRI检查，显示子宫颈有肿块，考虑宫颈鳞癌。
方法：阴道镜引导下宫颈活检及免疫组化证实CCAC，联合磁共振成像检查，考虑CCAC伴盆腔淋巴结转移。
结果：患者拒绝进一步治疗，出院。
结论：CCAC没有表现出特定的症状，在图像特征上与宫颈鳞癌略有不同，主要依靠免疫组织化学进行诊断。报告的病例提高了CCAC的认识。
