PDF(Pubmed)
Abstract：
Flaps are commonly used to repair large tissue defects caused by tumor resection and are often combined with radiotherapy. Relevant explanations for the mechanism underlying the effect of radiotherapy on flaps and the selection of the sequence of flaps and radiotherapy plan have emerged. The combination of flap and radiotherapy is most widely used in breast, head and neck cancers, while free flaps are the most widely used. Although, reduction of the incidence of complications of flap reconstruction, prevention of flap reconstruction failure and best integration of flap reconstruction with radiation therapy remains controversial. In the present review, these questions and debates were addressed by reviewing the literature on radiotherapy and flap reconstruction in cancer treatment.
摘要：
皮瓣常用于修复肿瘤切除引起的大型组织缺损，常与放疗联合使用。出现了关于放疗对皮瓣影响的潜在机制以及皮瓣序列和放疗计划的选择的相关解释。皮瓣和放疗的组合在乳腺中应用最广泛，头颈癌,而自由皮瓣是最广泛使用的。虽然,减少皮瓣重建并发症的发生率，预防皮瓣重建失败以及皮瓣重建与放射治疗的最佳整合仍存在争议。在本次审查中，通过回顾有关放疗和皮瓣重建在癌症治疗中的文献，解决了这些问题和争论。
