MYCN 通过与组蛋白甲基转移酶 G9a 和 WDR5 衔接子合作协调全局基因转录来驱动肿瘤发生。
Mesh : Humans Nuclear Proteins / metabolism N-Myc Proto-Oncogene Protein / genetics metabolism Histone Methyltransferases / genetics Cell Line, Tumor Cell Transformation, Neoplastic / genetics Carcinogenesis / genetics Gene Expression Regulation, Neoplastic Transcription, Genetic Intracellular Signaling Peptides and Proteins / genetics metabolism
来 源:
DOI:10.1371/journal.pbio.3002240
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