PDF(Pubmed)
Abstract：
UNASSIGNED: The purpose of this study was to investigate the spectral characteristics of choroidal nevi and assess the feasibility of quantifying the basal diameter of choroidal nevi using multispectral fundus images captured with trans-palpebral illumination.
UNASSIGNED: The study used a widefield fundus camera with multispectral (625 nm, 780 nm, 850 nm, and 970 nm) trans-palpebral illumination to examine eight subjects diagnosed with choroidal nevi. Geometric features of nevi, including border clarity, overlying drusen, and lesion basal diameter, were characterized. Clinical imagers, including scanning laser ophthalmoscopy (SLO), autofluorescence (AF), and optical coherence tomography (OCT), were utilized for comparative assessment.
UNASSIGNED: Fundus images depicted nevi as dark regions with high contrast against the background. Near-infrared (NIR) fundus images provided enhanced visibility of lesion borders compared to visible fundus images and SLO images. Lesion-background contrast measurements revealed 635 nm SLO at 11% and 625 nm fundus at 42%. Significantly enhanced contrasts were observed in NIR fundus images at 780 nm (73%), 850 nm (63%), and 970 nm (67%). For quantifying the diameter of nevi, NIR fundus images at 780 nm and 850 nm yielded a deviation of less than 10% when compared to OCT measurements.
UNASSIGNED: NIR fundus photography with trans-palpebral illumination enhances nevi visibility and boundary definition compared to SLO. Agreement in diameter measurements with OCT validates the accuracy and reliability of this method for choroidal nevi assessment.
UNASSIGNED: Multispectral fundus imaging with trans-palpebral illumination improves choroidal nevi visibility and accurately measures basal diameter, promising to enhance clinical practices in screening, diagnosis, and monitoring of choroidal nevi.
UNASSIGNED: The study used a widefield fundus camera with multispectral (625 nm, 780 nm, 850 nm, and 970 nm) trans-palpebral illumination to examine eight subjects diagnosed with choroidal nevi. Geometric features of nevi, including border clarity, overlying drusen, and lesion basal diameter, were characterized. Clinical imagers, including scanning laser ophthalmoscopy (SLO), autofluorescence (AF), and optical coherence tomography (OCT), were utilized for comparative assessment.
UNASSIGNED: Fundus images depicted nevi as dark regions with high contrast against the background. Near-infrared (NIR) fundus images provided enhanced visibility of lesion borders compared to visible fundus images and SLO images. Lesion-background contrast measurements revealed 635 nm SLO at 11% and 625 nm fundus at 42%. Significantly enhanced contrasts were observed in NIR fundus images at 780 nm (73%), 850 nm (63%), and 970 nm (67%). For quantifying the diameter of nevi, NIR fundus images at 780 nm and 850 nm yielded a deviation of less than 10% when compared to OCT measurements.
UNASSIGNED: NIR fundus photography with trans-palpebral illumination enhances nevi visibility and boundary definition compared to SLO. Agreement in diameter measurements with OCT validates the accuracy and reliability of this method for choroidal nevi assessment.
UNASSIGNED: Multispectral fundus imaging with trans-palpebral illumination improves choroidal nevi visibility and accurately measures basal diameter, promising to enhance clinical practices in screening, diagnosis, and monitoring of choroidal nevi.
摘要：
■这项研究的目的是研究脉络膜痣的光谱特征，并评估使用经睑照射捕获的多光谱眼底图像量化脉络膜痣基底直径的可行性。
■该研究使用了具有多光谱（625nm，780nm,850nm,和970nm）经睑照明，以检查八名诊断为脉络膜痣的受试者。痣的几何特征，包括边界清晰度，上面的玻璃疣，和病变基底直径，被表征。临床成像仪,包括扫描激光检眼镜（SLO），自发荧光(AF),光学相干断层扫描（OCT），用于比较评估。
■眼底图像将痣描绘为相对于背景具有高对比度的暗区域。与可见眼底图像和SLO图像相比,近红外(NIR)眼底图像提供病变边界的增强的可见性。病变-背景对比度测量显示，在11％时为635nmSLO，在42％时为625nm。在780nm（73％）的NIR眼底图像中观察到明显增强的对比度，850nm（63%），和970nm(67%)。为了量化痣的直径，当与OCT测量相比时,在780nm和850nm处的NIR眼底图像产生小于10%的偏差。
■与SLO相比，具有经睑照射的NIR眼底摄影增强了痣的可见性和边界清晰度。直径测量与OCT的一致性验证了该方法用于脉络膜痣评估的准确性和可靠性。
■采用经睑照射的多光谱眼底成像可改善脉络膜痣的可见度并精确测量基底直径，承诺加强筛查的临床实践，诊断,和监测脉络膜痣。
■该研究使用了具有多光谱（625nm，780nm,850nm,和970nm）经睑照明，以检查八名诊断为脉络膜痣的受试者。痣的几何特征，包括边界清晰度，上面的玻璃疣，和病变基底直径，被表征。临床成像仪,包括扫描激光检眼镜（SLO），自发荧光(AF),光学相干断层扫描（OCT），用于比较评估。
■眼底图像将痣描绘为相对于背景具有高对比度的暗区域。与可见眼底图像和SLO图像相比,近红外(NIR)眼底图像提供病变边界的增强的可见性。病变-背景对比度测量显示，在11％时为635nmSLO，在42％时为625nm。在780nm（73％）的NIR眼底图像中观察到明显增强的对比度，850nm（63%），和970nm(67%)。为了量化痣的直径，当与OCT测量相比时,在780nm和850nm处的NIR眼底图像产生小于10%的偏差。
■与SLO相比，具有经睑照射的NIR眼底摄影增强了痣的可见性和边界清晰度。直径测量与OCT的一致性验证了该方法用于脉络膜痣评估的准确性和可靠性。
■采用经睑照射的多光谱眼底成像可改善脉络膜痣的可见度并精确测量基底直径，承诺加强筛查的临床实践，诊断,和监测脉络膜痣。
