关键词: Hematology Malignancy Oncology Viral Viral oncology Virus

Mesh : Humans Herpesvirus 4, Human Epstein-Barr Virus Infections Neoplasms Viruses Hematologic Neoplasms

来  源:   DOI:10.1007/s12032-024-02345-1

Abstract:
Extensive research has been conducted on the correlation between viral infections and hematological cancers ever since the identification of the Rous Sarcoma Virus as a cancer-causing agent. Numerous viruses, such as the Epstein-Barr virus, hepatitis B virus, hepatitis C virus, human immunodeficiency virus, human T-lymphotropic virus 1, and severe acute respiratory syndrome-related coronavirus 2, have been identified as potential contributors to the development and progression of cancer by disrupting normal cellular processes. Different viruses are associated with distinct forms of blood cancers, each exhibiting unique infection mechanisms, pathogenesis, and clinical symptoms. Understanding these connections is crucial for the development of effective prevention and treatment strategies. Healthcare professionals who possess a solid understanding of these associations can offer precise treatments and closely monitor potential complications in individuals with blood cancers and viral infections. By leveraging this information, healthcare providers can optimize patient care and improve outcomes for those affected by both viral infections and hematological cancers.
摘要:
自从将劳斯肉瘤病毒鉴定为致癌因子以来,已经对病毒感染与血液癌症之间的相关性进行了广泛的研究。众多的病毒,比如爱泼斯坦-巴尔病毒,乙型肝炎病毒,丙型肝炎病毒,人类免疫缺陷病毒,人类嗜T淋巴细胞病毒1和严重急性呼吸综合征相关冠状病毒2已被确定为通过破坏正常细胞过程导致癌症发展和进展的潜在贡献者.不同的病毒与不同形式的血癌有关,每个都表现出独特的感染机制,发病机制,和临床症状。了解这些联系对于制定有效的预防和治疗策略至关重要。对这些关联有深入了解的医疗保健专业人员可以提供精确的治疗方法,并密切监测血液癌症和病毒感染患者的潜在并发症。通过利用这些信息,医疗保健提供者可以优化患者护理并改善受病毒感染和血液癌症影响的患者的预后。
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