PDF(Pubmed)
Abstract：
OBJECTIVE: Mastectomy, a common intervention for breast cancer, has substantial implications for a woman\'s quality of life (QoL). However, the literature on QoL outcomes following mastectomy-with or without breast reconstruction (BR) is scant. This study aims to assess and compare the QoL among Iraqi women post-mastectomy, examining the impacts of undergoing BR.
METHODS: We conducted a comprehensive cross-sectional study across multiple centers in Iraq from April to September 2021. Our cohort consisted of 404 women who had a mastectomy for breast cancer treatment, 154 of whom also chose to have BR. Utilizing the European Organisation for Research and Treatment of Cancer\'s (EORTC) tools specifically, select domains from EORTC QLQ-BR23, QLQ-C30, and QLQ-BRECON23-we evaluated various facets of their QoL.
RESULTS: The mean QoL score was 54 out of 100, with patients who did not undergo BR reporting slightly higher scores (55) compared to those who did (52). Notably, social and sexual functioning scores were statistically superior in the non-BR group. Satisfaction with surgery, sexual function, and breast aesthetics were the lowest rated aspects among BR patients, indicating a considerable gap between expectations and outcomes. Marital status and the type of mastectomy notably influenced body image and sexual function. A significant portion of patients (100 out of 250) opted out of BR due to recurrence concerns, while 26.2% (106 out of 154) pursued BR to restore their pre-mastectomy physique.
CONCLUSIONS: Contrary to the anticipated benefits of BR, our findings suggest that women who underwent the procedure reported a lower QoL compared to those who did not. The outcomes highlight the discrepancy between expected and actual benefits of BR, suggesting a pressing need for comprehensive rehabilitation programs. These programs should aim to enhance the QoL for post-mastectomy patients and provide in-depth counseling to align expectations with the potential realities of BR.
METHODS: We conducted a comprehensive cross-sectional study across multiple centers in Iraq from April to September 2021. Our cohort consisted of 404 women who had a mastectomy for breast cancer treatment, 154 of whom also chose to have BR. Utilizing the European Organisation for Research and Treatment of Cancer\'s (EORTC) tools specifically, select domains from EORTC QLQ-BR23, QLQ-C30, and QLQ-BRECON23-we evaluated various facets of their QoL.
RESULTS: The mean QoL score was 54 out of 100, with patients who did not undergo BR reporting slightly higher scores (55) compared to those who did (52). Notably, social and sexual functioning scores were statistically superior in the non-BR group. Satisfaction with surgery, sexual function, and breast aesthetics were the lowest rated aspects among BR patients, indicating a considerable gap between expectations and outcomes. Marital status and the type of mastectomy notably influenced body image and sexual function. A significant portion of patients (100 out of 250) opted out of BR due to recurrence concerns, while 26.2% (106 out of 154) pursued BR to restore their pre-mastectomy physique.
CONCLUSIONS: Contrary to the anticipated benefits of BR, our findings suggest that women who underwent the procedure reported a lower QoL compared to those who did not. The outcomes highlight the discrepancy between expected and actual benefits of BR, suggesting a pressing need for comprehensive rehabilitation programs. These programs should aim to enhance the QoL for post-mastectomy patients and provide in-depth counseling to align expectations with the potential realities of BR.
摘要：
目的：乳房切除术，乳腺癌的常见干预措施，对女性的生活质量(QoL)有重大影响。然而,关于乳房切除术后QoL结局的文献很少-有或没有乳房再造(BR).这项研究旨在评估和比较伊拉克女性乳房切除术后的生活质量，检查接受BR的影响。
方法：我们于2021年4月至9月在伊拉克的多个中心进行了全面的横断面研究。我们的队列包括404名接受乳腺癌切除术的女性，其中154人也选择了BR。特别是利用欧洲癌症研究和治疗组织(EORTC)工具，从EORTCQLQ-BR23，QLQ-C30和QLQ-BRECON23中选择域-我们评估了其QoL的各个方面。
结果：平均QoL评分为100分中的54分，未接受BR的患者的评分（55）略高于接受BR的患者（52）。值得注意的是,非BR组的社会和性功能评分在统计学上优于对照组.对手术满意,性功能,和乳房美学是BR患者中评价最低的方面，表明预期和结果之间存在相当大的差距。婚姻状况和乳房切除术的类型显着影响身体形象和性功能。很大一部分患者（250人中有100人）因复发而选择退出BR，而26.2％（154人中有106人）追求BR以恢复乳房切除术前的体格。
结论：与BR的预期益处相反，我们的研究结果表明,接受手术的女性报告的QoL低于未接受手术的女性.结果突出了BR的预期收益和实际收益之间的差异，这表明迫切需要全面的康复计划。这些计划应旨在提高乳房切除术后患者的QoL，并提供深入的咨询，以使期望与BR的潜在现实保持一致。
方法：我们于2021年4月至9月在伊拉克的多个中心进行了全面的横断面研究。我们的队列包括404名接受乳腺癌切除术的女性，其中154人也选择了BR。特别是利用欧洲癌症研究和治疗组织(EORTC)工具，从EORTCQLQ-BR23，QLQ-C30和QLQ-BRECON23中选择域-我们评估了其QoL的各个方面。
结果：平均QoL评分为100分中的54分，未接受BR的患者的评分（55）略高于接受BR的患者（52）。值得注意的是,非BR组的社会和性功能评分在统计学上优于对照组.对手术满意,性功能,和乳房美学是BR患者中评价最低的方面，表明预期和结果之间存在相当大的差距。婚姻状况和乳房切除术的类型显着影响身体形象和性功能。很大一部分患者（250人中有100人）因复发而选择退出BR，而26.2％（154人中有106人）追求BR以恢复乳房切除术前的体格。
结论：与BR的预期益处相反，我们的研究结果表明,接受手术的女性报告的QoL低于未接受手术的女性.结果突出了BR的预期收益和实际收益之间的差异，这表明迫切需要全面的康复计划。这些计划应旨在提高乳房切除术后患者的QoL，并提供深入的咨询，以使期望与BR的潜在现实保持一致。
